ArticleNature communications2026
Developmental origins of exceptional health and survival: a four-generation family cohort study.
Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Familial healthy aging and longevity: the role of spouses.BMC medicine · 2026Article
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9 authors.
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Abstract
Descendants of longevity-enriched sibships demonstrate a broad health and survival advantage throughout the life course. However, little is known about manifestations during very early life. Here we show a pattern of lower risk of adverse early-life outcomes in third-generation grandchildren (N = 5637) of Danish longevity-enriched sibships compared to the general population, including infant mortality (Hazard Ratio = 0.53, 95% CI [0.36, 0.77]) and a range of neonatal health indicators. These associations in fourth-generation great-grandchildren (N = 14,908) were attenuated and less consistent (e.g., infant mortality, Hazard Ratio = 0.90, [0.70, 1.17]). Dilatory patterns across successive generations were independent of stable advantages in select socioeconomic and behavioural indicators (e.g., parental education, income and maternal smoking), maternal and paternal lines of transmission, as well as secular trends in the background population. However, our socioeconomic and behavioral indicators were limited in both range and granularity. Our findings suggest that the familial aggregation of exceptional health and survival has early life developmental components.
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