ArticleJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2026
Global trends in norovirus genotype distribution among medically attended children with acute gastroenteritis, 2020-2025.
Article in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
42 authors.
Funding
Abstract
backgroundNorovirus is a leading cause of acute gastroenteritis, with a broad diversity of genotypes infecting children. NoroSurv is an established global network for norovirus strain surveillance among medically attended children < 5 years of age.
methodsParticipating laboratories uploaded norovirus sequences from stool specimens collected from 2020 to 2025 to a web portal, which assigned norovirus genotypes and strain data. Norovirus seasons were defined as September 1 to August 31.
resultsParticipants in 22 countries across 6 continental regions uploaded 4113 norovirus sequences, including 26 genotypes and 53 strains. GII.4 accounted for 53% (2167/4113), followed by GII.3 (12%), GII.17 (11%), GII.6 (7%), and GII.2 (5%). GII.4 Sydney was the most common variant (47%; 1912/4113), but new GII.4 variants/clusters emerged regionally, with GII.4 San Francisco, GII.4 Wichita and GII.4 Allegany more frequently detected than GII.4 Sydney in 2021-2022 in Africa, 2022-2023 in Central and South America and 2023-2024 in Central America. In 2023-2024, a dramatic rise in GII.17 detection was observed in most regions (32% of all 2024-2025 sequences). In North, Central and South America, Europe and Asia Pacific, GII.17 detection increased as GII.4 detection declined in 2024-2025. Other genotypes (GI.3, GII.1, GII.2, GII.3 and GII.6) had regional peaks, accounting for up to 37% of sequences during a specific season.
conclusionsOur data may help guide norovirus vaccine development and provide a baseline of global norovirus strain distribution for evaluating the effectiveness of future vaccines in children. We continue to monitor the shifting distribution of norovirus genotypes through NoroSurv surveillance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.