Evidence map›Paper›PMID 42105426›Full record

ArticleAtencion primaria2026

Comprehensive analysis of heart failure: Characteristics, treatment, and outcomes in a reduced ejection fraction patient cohort from SIDIAP, Catalonia, Spain.

Maria Giner-Soriano, Ramon Monfà, Roser Vives, Silvia Fernández-García, Antoni Vallano, Rosa Morros

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Article in Atencion primaria, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Maria Giner-SorianoFundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain; Universitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Spain. Electronic address: mginer@idiapjgol.info.
Ramon MonfàFundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain; Universitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Spain.
Roser VivesMedicines Department, Catalan Healthcare Service, Barcelona, Spain; Department of Pharmacology, Therapeutics and Toxicology, Universitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Spain.
Silvia Fernández-GarcíaFundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain; Department of Pharmacology, Therapeutics and Toxicology, Universitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Spain; Department of Medical Sciences, Universitat de Girona, Girona, Spain.
Antoni VallanoMedicines Department, Catalan Healthcare Service, Barcelona, Spain; Department of Pharmacology, Therapeutics and Toxicology, Universitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Spain; Institut Català de la Salut, Barcelona, Spain.
Rosa MorrosFundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain; Department of Pharmacology, Therapeutics and Toxicology, Universitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Spain; Institut Català de la Salut, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe sociodemographic and clinical characteristics, treatments, and incidence of hospital admission and all-cause mortality within a cohort of patients diagnosed with heart failure with reduced ejection fraction (HFrEF) followed up in Primary Care.

designPopulation-based cohort study. SITE: The data source is the Information System for the Development of Research in Primary Care (SIDIAP), which captures information from the Electronic Health Records of Primary Health Care of the Catalan Institute of Health (approximately 80% of the Catalan population).

participantsAdults with a diagnostic code of HFrEF in 2018-2022.

interventionsNot applicable. MAIN MEASUREMENTS: Socio-demographic and clinical characteristics, drug exposure, hospitalizations due to heart failure and all-cause mortality.

resultsWe included 17,169 patients; 59.5% men and 40.5% women. We found differences between men and women in clinical characteristics and in drug combinations, and suboptimal use to recommended therapies, being better for men than for women. Women had higher hospitalization (44.6% vs 42.1%) and all-cause mortality rates (27.2% vs 25.3%). Hazard ratio of hospitalization was higher in older than 60, with increasing NYHA, diabetic patients and in previously hospitalized.

conclusionsWe observed sex disparities in baseline characteristics, in drug use for heart failure, and in adherence to treatment recommendations. Women had higher rates of hospital admissions and all-cause mortality, although the hazard ratio for hospitalization risk was similar between sexes. Age over 60, increasing NHYA, diabetes and prior heart-failure hospitalization resulted in higher risk of hospital admission. These findings highlight the importance of tailoring treatment strategies according to clinical conditions.

Indexed as

Heart FailureStroke VolumeAgedAged, 80 and overCohort StudiesFemaleHospitalizationHumansMaleMiddle AgedPrimary Health CareSpainTreatment OutcomeAtención primariaElectronic health recordsFracción de eyección del ventrículo izquierdoHeart failureHeart failure with reduced ejection fractionInsuficiencia cardíacaInsuficiencia cardíaca con fracción de eyección reducidaLeft ventricular ejection fractionPrimary health careRegistros electrónicos de salud

Identifiers

PMID42105426
PMCPMC13187961

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.