Evidence map›Paper›PMID 42105354›Full record

ArticleChemistry & biodiversity2026

Synthesis and Characterization of Mannich-Derived 1,4-Naphthoquinones From Lawsone: Photophysical Properties, Molecular Docking, BSA/DNA Interactions, and Antioxidant Activity.

Yavuz Derin, Büşra Albayrak Misir, Özge Güngör, Seyit Ali Güngör, Raşit Fikret Yilmaz, Taoufik Rohand, Ahmet Tutar

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yavuz DerinFaculty of Science, Department of Chemistry, Sakarya University, Sakarya, Türkiye.ORCID https://orcid.org/0000-0002-4935-2678
Büşra Albayrak MisirFaculty of Science, Chemistry Department, Kahramanmaras Sutcu Imam University, Kahramanmaras, Türkiye.
Özge GüngörFaculty of Science, Chemistry Department, Kahramanmaras Sutcu Imam University, Kahramanmaras, Türkiye.
Seyit Ali GüngörFaculty of Science, Chemistry Department, Kahramanmaras Sutcu Imam University, Kahramanmaras, Türkiye.
Raşit Fikret YilmazDepartment of Fundamental Sciences, National Defence University, Turkish Naval Academy, Tuzla, İstanbul, Türkiye.
Taoufik RohandApplied Chemistry Team, Faculty of Sciences & Techniques Al-Hoceima, Abdelmalek Essaâdi University, Tetouan, Morocco.
Ahmet TutarFaculty of Science, Department of Chemistry, Sakarya University, Sakarya, Türkiye.

Funding

Sakarya University Scientific Research Foundation 2021-7-25-5
6 · The paper itself

Abstract

The present study focuses on the synthesis of eight novel 2-hydroxy-1,4-naphthoquinone (lawsone) derivatives in moderate to high yields (31%-90%) via the Mannich reaction. The structures of the synthesized compounds (1-8) were characterized using a combination of analytical techniques, including HRMS, as well as

Indexed as

AntioxidantsDNAMolecular Docking SimulationNaphthoquinonesSerum Albumin, BovineAnimalsBinding SitesCattleMannich BasesMolecular StructureStructure-Activity Relationship1,4-naphthoquinoneAntioxidantsDNAlawsoneMannich BasesNaphthoquinonesSerum Albumin, Bovine1,4‐naphthoquinoneantioxidantBSA bindingDNA bindingMannich reactionmolecular docking

Identifiers

PMID42105354
PMCPMC13381013

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.