ReviewBrain, behavior and evolution2026
The Impact of Developmental and Genetic Influences on Neural Circuits.
Review in Brain, behavior and evolution, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
backgroundNeural circuits form the basis for brain function and behavior. However, solely focusing on adult brains can sometimes overlook prior events that may have shaped this anatomy. These other perspectives can provide further insight into brain circuit organization. SUMMARY: To support this suggestion, specific examples of developmental and genetic events are presented that might not be appreciated if only adult brains were investigated. Examples include the following. One is the origin of nuclei from the same developmental field that divides into major subdivisions. Each of the resulting areas has neurons with different morphology, connections, and molecular signatures. The other is new circuit formation that is produced in three ways. One is the result of peripheral sensory receptor reduction. Another is the consequence of genetic mutation. The third is due to axonal pruning or perinatal injury. KEY MESSAGE: In certain instances, developmental and genetic features provide additional perspectives to better understand how circuit formation in the brains of adult animals came to be.
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