Evidence map›Paper›PMID 42104986›Full record

ReviewChemical biology & drug design2026

Fucoidan: An Update on Function, Role in Human Health and Applications.

Sharon Critelli, Marilena Celano

Abstract readReview
In one paragraph

Review in Chemical biology & drug design, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sharon CritelliDepartment of Health Sciences, University "Magna Graecia" of Catanzaro, Catanzaro, Italy.
Marilena CelanoDepartment of Health Sciences, University "Magna Graecia" of Catanzaro, Catanzaro, Italy.

Funding

Università degli Studi Magna Graecia di Catanzaro; Dipartimento di Scienze della Salute
6 · The paper itself

Abstract

Fucoidan is a polysaccharide bioactive compound, mainly from brown algae, characterized by multiple biological activities, including anti-inflammatory, anticoagulant, anticancer, antioxidant, antiviral, and cardioprotective properties. In addition, growing scientific evidence supports its epigenetic potential and ability to modulate autophagic mechanisms, two crucial aspects for the treatment and prevention of chronic diseases, such as cancer, inflammation, and aging. For this reason, Fucoidan is a promising candidate for a wide range of applications, both as a bioactive component of drug delivery systems in order to improve their stability, bioavailability, and potentially reduce their side effects, and as an adjuvant in drug therapies. The aim of this review is to provide an update on the correlation between properties and distinctive chemical characteristics, to underline an interesting emerging role in epigenetics and autophagy and to be a new key point for preclinical and clinical studies, in order to better understand their properties and possible new therapeutic and biomedical applications.

Indexed as

PolysaccharidesAnimalsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsAutophagyEpigenesis, GeneticHumansNeoplasmsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsfucoidanPolysaccharidesadjuvantanticancerantioxidantautophagydrug delivery systemepigeneticexosomesfucoidan

Identifiers

PMID42104986
PMCPMC13157028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.