Evidence map›Paper›PMID 42104931›Full record

ArticleThe oncologist2026

Reframing sperm cryopreservation in male cancer survivors: from procedural success to meaningful utilization.

Andrea Garolla

Abstract readEditorialComment
In one paragraph

Article in The oncologist, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Andrea GarollaUnit of Andrology and Reproductive Medicine & Centre for Male Gamete Cryopreservation, Department of Medicine, University Hospital of Padova, Padova, 35128, Italy.ORCID 0000-0003-4736-9051

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The expert review by Alexander and colleagues addresses a long-standing yet insufficiently interrogated paradox in contemporary oncofertility item: While sperm cryopreservation prior to gonadotoxic cancer therapy is widely endorsed, technically straightforward, and increasingly accessible, its subsequent utilization by male cancer survivors remains consistently low. This discrepancy, persisting across institutions, health-care systems, and decades, suggests that the challenge is no longer primarily technical or educational, but structural, temporal, and psychosocial in nature. The central merit of this review lies in its deliberate shift away from a narrow, procedure-centered conception of fertility preservation toward a longitudinal, survivorship-oriented framework. In doing so, the authors implicitly challenge the field to reconsider what constitutes "success" in oncofertility. If success is defined merely as successful banking prior to treatment, then current practice may appear satisfactory. If, however, success is defined as enabling informed, autonomous, and timely reproductive decision-making across the survivorship trajectory, then the low utilization rates described in this review represent a clear failure of care continuity.

Indexed as

Cancer SurvivorsCryopreservationFertility PreservationNeoplasmsSemen PreservationSpermatozoaHumansMaleSurvivors

Identifiers

PMID42104931
PMCPMC13167791

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.