Evidence map›Paper›PMID 42104855›Full record

ArticleOrthodontics & craniofacial research2026

The 'Roller Coaster Effect' in Clear Aligner Premolar Extraction Cases: Posterior Open Bite and Cephalometric Risk Factors.

Yujia Zhuo, Feng Guo, Shuai Huang, Lang Lei

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Article in Orthodontics & craniofacial research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Yujia ZhuoDepartment of Orthodontics, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing, China.
Feng GuoDepartment of Orthodontics, Stomatological Hospital Affiliated Suzhou Vocational Health College, Suzhou, China.ORCID https://orcid.org/0009-0001-3807-6399
Shuai HuangDepartment of Orthodontics, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing, China.
Lang LeiDepartment of Orthodontics, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing, China.ORCID https://orcid.org/0009-0004-3574-0321

Funding

High-Level Hospital Construction Project of Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University 0224C015National Natural Science Foundation of China 82371007
6 · The paper itself

Abstract

objectivesThis study aimed to investigate the occurrence of the roller coaster effect (RCE) in premolar extraction cases treated with clear aligner therapy (CAT), and to identify cephalometric risk factors. MATERIALS AND

methodsSixty five patients treated with CAT after four first premolar extractions were retrospectively analysed, including 34 with mild crowding (Mi) and 31 with moderate-severe crowding (Mo-Se). Posterior functional cusp distances (FCDs) were measured at the second premolar, mandibular first molar mesiobuccal (MB) and distobuccal (DB) cusps, and second molar on pre- and post-treatment digital models using a standardised 3D coordinate system.

resultsAs mesial molar movement was minimal in this cohort, post-treatment FCDs increased significantly in the Mi group at all posterior sites, with the greatest changes at the first molars (MB: 1.64 ± 1.39 mm; DB: 1.48 ± 1.55 mm; both p < 0.001), while the Mo-Se group showed an increase only at the first molar MB cusp (p < 0.001). Comparisons indicated greater FCDs increases in the Mi group than in the Mo-Se group (all p < 0.05). Correlation analysis revealed positive associations between greater upper incisor proclination (U1-NA, U1-SN) and posterior FCDs increases. The regression analysis further identified a smaller ANB angle as an independent risk factor for RCE.

conclusionsPosterior FCDs served as a simple and clinically applicable indicator of RCE, most pronounced at the first molars and in mild crowding cases. Smaller ANB angles and increased maxillary incisor proclination were associated with higher RCE susceptibility, emphasising prudent case selection in extraction-based clear aligner therapy.

Indexed as

BicuspidCephalometryOpen BiteOrthodontic Appliances, RemovableTooth ExtractionTooth Movement TechniquesAdolescentChildFemaleHumansMaleMalocclusionMolarRetrospective StudiesRisk Factorsclear aligner therapyfunctional cusp distancepremolar extractionroller coaster effect

Identifiers

PMID42104855
PMCPMC13543194

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.