Evidence map›Paper›PMID 42104720›Full record

ArticleFuture microbiology2026

Assessing antimicrobial resistance in Shiga toxin-producing

Tarjani Bhatt, Csaba Varga

Abstract read
In one paragraph

Article in Future microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Tarjani BhattDepartment of Health and Kinesiology, University of Illinois Urbana-Champaign, Urbana, IL, USA.ORCID 0009-0004-6349-7816
Csaba VargaDepartment of Pathobiology, College of Veterinary Medicine, University of Illinois Urbana-Champaign, Urbana, IL, USA.ORCID 0000-0003-2751-3677

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo characterize antimicrobial resistance (AMR) patterns and temporal trends among Shiga toxin-producing PATIENTS AND

methods1,995 STEC O157 isolates collected from cases between 2010 and 2021 were analyzed. Resistance to antimicrobials was assessed, and temporal trends were evaluated using the Mann-Kendall test. Associations between AMR and demographic factors, including age and region, were examined using logistic regression models.

resultsResistance was most common to tetracycline (12.4%) and sulfisoxazole (9.9%), with temporal increases observed in resistance for these agents, along with chloramphenicol and trimethoprim-sulfamethoxazole (Mann-Kendall tau = 0.69-0.87,

conclusionsSince antimicrobials are not recommended for treating STEC O157 infections in humans, the sources of resistant strains could be foodborne, direct animal contact, the environment, or treatment for bacterial coinfections. The increase in the prevalence of AMR among STEC O157 strains in humans warrants investigation into the factors driving the emergence of resistant isolates. These findings call for an "One Health" approach for antimicrobial stewardship to mitigate AMR risks.

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialDrug Resistance, Multiple, BacterialEscherichia coli InfectionsEscherichia coli O157AdolescentAdultAgedChildChild, PreschoolFemaleHumansInfantMaleMicrobial Sensitivity TestsMiddle AgedAnti-Bacterial AgentsTrimethoprim, Sulfamethoxazole Drug CombinationAntimicrobial resistanceantimicrobial stewardshipclinical isolatesE. coli O157foodborne infectiontemporal trends

Identifiers

PMID42104720
PMCPMC13228943

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.