ArticleJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine2026
Non-invasive Reduction of Accessory Breast Fat Using Multilayer High-Intensity Focused Ultrasound: A Quantitative Ultrasound-Based Study.
Article in Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesAccessory breast tissue often presents as localized axillary subcutaneous fullness, presenting as a palpable soft-tissue bulge composed of adipose or glandular elements, causing mechanical discomfort and esthetic concern. While surgical excision remains effective, it ma result in scarring, postoperative pain, and risks of seroma/hematoma or contour irregularity, leading to growing interest in noninvasive approaches. The objective of the study is to investigate the effect of noninvasive high-intensity focused ultrasound (HIFU) on subcutaneous fat thickness in axillary accessory breast tissue.
methodsThis prospective study enrolled 30 women with BMI ≥27 kg/m
resultsAmong the 28 participants who completed the 8-week follow-up, mean subcutaneous fat thickness decreased from 19.2 ± 3.4 mm at baseline to 15.8 ± 3.1 mm at 8 weeks. The mean paired reduction was 3.4 ± 1.6 mm (17.7%), which was statistically significant (95% CI, 2.8-4.0 mm; p = 1.1 × 10⁻¹¹). All participants showed GAIS improvement with high satisfaction. No serious adverse events were observed; mild and transient effects included transient thermal discomfort and localized erythema resolving within several hours to 2 days, and no cases of skin burn were identified.
conclusionNon-invasive HIFU produced a measurable reduction of accessory breast fat with favorable esthetic outcomes and an acceptable safety profile.
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