Evidence map›Paper›PMID 42104438›Full record

ArticleNutrition & metabolism2026

Association of pericardial fat volume with risk of incident type 2 diabetes mellitus or major adverse cardiovascular events: Evidence from UK Biobank cohort study.

Feng Hu, Jing Wang, Xinjie Zeng, Hui Chen, Chaoyang Lin, Fayuan Fu, Lin Fan

Abstract read
In one paragraph

Article in Nutrition & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Feng Hu *Department of Cardiology, Fujian Medical University Union Hospital, Fujian Cardiovascular Medical Center, Fujian Institute of Coronary Artery Disease, Fujian Cardiovascular Research Center, Fuzhou, 350001, PR China.
Jing Wang *Department of Cardiology, Fujian Medical University Union Hospital, Fujian Cardiovascular Medical Center, Fujian Institute of Coronary Artery Disease, Fujian Cardiovascular Research Center, Fuzhou, 350001, PR China.
Xinjie ZengDepartment of Cardiology, Fujian Medical University Union Hospital, Fujian Cardiovascular Medical Center, Fujian Institute of Coronary Artery Disease, Fujian Cardiovascular Research Center, Fuzhou, 350001, PR China.
Hui ChenDepartment of Cardiology, Fujian Medical University Union Hospital, Fujian Cardiovascular Medical Center, Fujian Institute of Coronary Artery Disease, Fujian Cardiovascular Research Center, Fuzhou, 350001, PR China.
Chaoyang LinDepartment of Cardiology, Fujian Medical University Union Hospital, Fujian Cardiovascular Medical Center, Fujian Institute of Coronary Artery Disease, Fujian Cardiovascular Research Center, Fuzhou, 350001, PR China.
Fayuan FuDepartment of Cardiology, Fujian Medical University Union Hospital, Fujian Cardiovascular Medical Center, Fujian Institute of Coronary Artery Disease, Fujian Cardiovascular Research Center, Fuzhou, 350001, PR China. 1874058007@qq.com.
Lin FanDepartment of Cardiology, Fujian Medical University Union Hospital, Fujian Cardiovascular Medical Center, Fujian Institute of Coronary Artery Disease, Fujian Cardiovascular Research Center, Fuzhou, 350001, PR China. rickfan7587@hotmail.com.

Funding

the Key Discipline Construction Program of Traditional Chinese Medicine in Fujian Province NO.2024-363the Science and Technology Innovation Joint Fund Project of Fujian Provincial Science and Technology Department 2020Y9068, 2023Y9183
6 · The paper itself

Abstract

backgroundThis study seeks to investigate the relationship between pericardial fat volume and the risk of developing type 2 diabetes mellitus (T2DM) and major adverse cardiovascular events (MACE).

methodsThe analysis included a cohort of 39, 125 participants from the UK Biobank. The associations between the mean estimate pericardial fat area (MEPFA), as measured by cardiac magnetic resonance imaging, and the incidence of T2DM and MACE were evaluated using multivariable Cox proportional hazards regression models and Kaplan-Meier survival curves.

resultsThere were 343 occurrences of new-onset T2DM and 1, 894 occurrences of new-onset MACE over a median follow-up period of 55 months. Compared with patients with MEPFA ≤ 13.80 cm

conclusionsThe findings indicated that elevated MEPFA levels were significantly and independently associated with the onset of T2DM and MACE. Preliminary results suggested that increased levels of pericardial fat might enhance the predictive capability for cardio-metabolic risk.

Indexed as

Major adverse cardiovascular eventsMean estimate pericardial fat areaPericardial fat volumeType 2 diabetes mellitusUK Biobank

Identifiers

PMID42104438
PMCPMC13330092

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.