Evidence map›Paper›PMID 42104163›Full record

SynthesisChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2026

Postoperative raised ICP after minimally invasive surgery for monosutural craniosynostosis.

Renata Martinelli, Miriana Cusumano, Gianpiero Tamburrini, Luca Massimi

Abstract readSystematic Review
In one paragraph

Synthesis in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Renata MartinelliPediatric Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Miriana CusumanoPediatric Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Gianpiero TamburriniPediatric Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Luca MassimiPediatric Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. luca.massimi@policlinicogemelli.it.ORCID 0000-0003-3088-0822

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMinimally invasive craniectomies (MIC) for monosutural craniosynostosis are more and more used. Their results are usually investigated in terms of surgical, esthetic, and neuropsychological outcomes but not specifically about the risk of postoperative raised intracranial pressure (ICP). The goal of this article is to review the literature and the personal experience looking for the possible risk of postoperative raised ICP after MIC.

methodsA systematic review adhering to PRISMA guidelines was realized. In parallel, the personal experience concerning scaphocephalic children consecutively operated on between 2010 and 2013 by MIC was analyzed. Children operated on by open cranial vault remodeling (OCVR) in the same period were considered as controls.

resultsOverall, 3048 patients from 14 studies were included, 5% of them requiring a reoperation after a 59.9-month mean follow-up. A total of 2297 children were treated by MIC: 2.8% (65 cases) showed postoperative raised ICP, the rate of reoperation was 4.4% (102 cases). The risk of reoperation varies across the techniques, being higher in modified or spring-assisted strip craniectomies (2.4-14.6%) than in endoscopy-assisted craniectomies (2.4%). Among 751 cases treated by OCVR, this risk varied from 0.95 to 7.1%. Also in the personal experience, no significant differences were found between MIC (1.5% of reoperation for raised ICP) and OCVR (0.8%).

conclusionsThe risk of postoperative raised ICP seems to be relatively low after surgery for monosutural synostosis without a significant difference between MIC and OCVR. Missing standardized methods for postoperative screening, missing information about the reason of reoperation in some studies, and the retrospective analysis methods in most of them are the main limitations of this study.

Indexed as

CraniosynostosesCraniotomyIntracranial HypertensionMinimally Invasive Surgical ProceduresPostoperative ComplicationsHumansInfantReoperationCraniosynostosisIntracranial pressureMinimally invasive surgeryScaphocephalyStrip craniectomies

Identifiers

PMID42104163
PMCPMC13156180

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.