Evidence map›Paper›PMID 42104149›Full record

ReviewJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2026

Special feature: "current status and future development of organ preservation technology" novel techniques for assessing pulmonary function in cellular ex vivo lung perfusion: a republication of the review published in Japanese Journal of Artificial Organs.

Ryo Kosaka, Daisuke Sakota, Hiromichi Niikawa, Yoshinori Okada, Tetsuhito Kigata, Katsuhiro Ohuchi, Eiki Nagaoka, Tomoyuki Fujita, Ichiro Sakanoue, Toshihiro Okamoto

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PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ryo KosakaHealth and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-2-1 Namiki, Tsukuba, 305-8564, Ibaraki, Japan. ryo.kosaka@aist.go.jp.ORCID http://orcid.org/0000-0002-4658-6196
Daisuke SakotaHealth and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-2-1 Namiki, Tsukuba, 305-8564, Ibaraki, Japan.
Hiromichi NiikawaThoracic Surgery, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi, Japan.
Yoshinori OkadaDepartment of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Miyagi, Japan.
Tetsuhito KigataLaboratory of Veterinary Anatomy, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, Japan.
Katsuhiro OhuchiDepartment of Clinical Engineering, Faculty of Medical Science, Juntendo University, Urayasu, Chiba, Japan.
Eiki NagaokaDepartment of Cardiovascular Surgery, Institute of Science Tokyo, Bunkyo-ku, Tokyo, Japan.
Tomoyuki FujitaDepartment of Cardiovascular Surgery, Institute of Science Tokyo, Bunkyo-ku, Tokyo, Japan.
Ichiro SakanoueDepartment of Thoracic Surgery, Kyoto University, Kyoto, Kyoto, Japan.
Toshihiro OkamotoDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung transplantation is the definitive therapy for end-stage respiratory diseases. To expand the donor lung pool, ex vivo lung perfusion (EVLP) has been developed for the assessment of marginal donor lungs. However, current evaluation methods remain limited. This study aimed to develop non-invasive imaging and monitoring techniques for the quantitative and early assessment of pulmonary function during EVLP. Three novel approaches were established: (1) lung thermography during the initial reperfusion period to assess pulmonary function, (2) optical oxygen saturation (SaO₂) imaging to assess pulmonary oxygenation, and (3) real-time lung weight measurement as an early indicator of transplant suitability. Lung thermography revealed that lung surface temperature at 8 min after shunt closure was significantly lower in non-suitable cases than in suitable cases (25.1 ± 0.6 °C vs. 27.8 ± 1.2 °C, P < 0.01). Optical SaO₂ imaging demonstrated a strong correlation between lower lobe SaO₂ calculated from SaO₂ imaging and PaO

Indexed as

Artificial OrgansLungLung TransplantationOrgan PreservationPerfusionHumansJapanOxygenThermographyOxygenEx vivo lung perfusionLung thermographyOptical oxygen saturation imagingPulmonary function assessmentReal-time lung weight measurement

Identifiers

PMID42104149
PMCPMC13156164

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.