Evidence map›Paper›PMID 42104085›Full record

ReviewMicrobial ecology2026

Medium- and Large-sized Mammals on the Plateau: An Evolutionary Crucible for Zoonotic Pathogens - Ecological Drivers, Adaptive Evolution, and One Health Control.

Sha Tan, Jishan Wang, Afito Luciano, Jiani Li, Yuxin Huo, Yuting Ma, Jie Yang, Jiahao Guo, Bing Zhang, Xia He and 2 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Microbial ecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sha TanSchool of Basic Medical Sciences, Central South University, Changsha, 410013, China.
Jishan WangSouthwest Survey and Planning Institute of National Forestry and Grassland Administration, Yunnan, 650031, China.
Afito LucianoSchool of Basic Medical Sciences, Central South University, Changsha, 410013, China.
Jiani LiSchool of Basic Medical Sciences, Central South University, Changsha, 410013, China.
Yuxin HuoSchool of Basic Medical Sciences, Central South University, Changsha, 410013, China.
Yuting MaSchool of Basic Medical Sciences, Central South University, Changsha, 410013, China.
Jie YangSchool of Basic Medical Sciences, Central South University, Changsha, 410013, China.
Jiahao GuoSchool of Basic Medical Sciences, Xinjiang Medical University, Urumqi, 830017, China.
Bing ZhangSchool of Basic Medical Sciences, Xinjiang Medical University, Urumqi, 830017, China.
Xia HeSouthwest Survey and Planning Institute of National Forestry and Grassland Administration, Yunnan, 650031, China.
Mingxu ZhaoSouthwest Survey and Planning Institute of National Forestry and Grassland Administration, Yunnan, 650031, China.
Fanming MengSchool of Basic Medical Sciences, Central South University, Changsha, 410013, China. mengfanming1984@163.com.

Funding

the National Natural Science Foundation of China 32370554 and 32460248
6 · The paper itself

Abstract

Plateau regions have emerged as pivotal epicenters of diverse zoonoses because of their distinctive ecological conditions and rich biodiversity. Against the backdrop of intensifying climate change, escalating interactions between wildlife, livestock, and humans, and expanding human activities, these regions now face formidable challenges. To assess public health threats within plateau ecosystems and establish targeted prevention frameworks, this review systematically synthesizes the prevalence and potential cross-species transmission risks of zoonotic pathogens-spanning parasites, viruses, and bacteria-carried by large- and medium-sized wild mammals across China's four major plateaus (Tibetan Plateau, Yunnan-Guizhou Plateau, Loess Plateau, and Inner Mongolia Plateau). Critical issues, including ecological fragility, complexity of pathogen transmission networks, and delayed responsiveness of control measures, are comprehensively analyzed. Future strategies must embrace the One Health concept to construct a multidimensional, coordinated prevention system. By integrating pathogen surveillance, ecological regulation, and technological innovation, a refined zoonosis control framework anchored in safeguarding plateau biosafety and public health can be systematically advanced.

Indexed as

MammalsOne HealthZoonosesAnimalsAnimals, WildBiological EvolutionChinaEcosystemHumansOne healthPathogen transmissionPlateau regionsWildlifeZoonotic diseases

Identifiers

PMID42104085
PMCPMC13323216

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.