Evidence map›Paper›PMID 42104020›Full record

ArticleDiscover oncology2026

The effect of delays in cancer surgery due to the COVID-19 pandemic on cancer resectability and postoperative mortality in different tumor entities.

Antonia L Stengler, Jörg Kleeff, Lisa Rieder, James C Glasbey, Aneel A Bhangu, Ewen M Harrison, Ulrich Ronellenfitsch, CovidSurg Collaborative

Erratum issuedAbstract read
In one paragraph

Article in Discover oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Antonia L StenglerDepartment of Visceral, Vascular and Endocrine Surgery, University Hospital Halle (Saale) and Medical Faculty of the Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Straße 40, 06120, Halle (Saale), Germany.
Jörg KleeffDepartment of Visceral, Vascular and Endocrine Surgery, University Hospital Halle (Saale) and Medical Faculty of the Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Straße 40, 06120, Halle (Saale), Germany.
Lisa RiederDepartment of Visceral, Vascular and Endocrine Surgery, University Hospital Halle (Saale) and Medical Faculty of the Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Straße 40, 06120, Halle (Saale), Germany.
James C GlasbeyUniversity of Birmingham, Birmingham, B15 2TT, UK.
Aneel A BhanguUniversity of Birmingham, Birmingham, B15 2TT, UK.
Ewen M HarrisonOld College, University of Edinburgh, South Bridge, Edinburgh, EH8 9YL, UK.
Ulrich RonellenfitschDepartment of Visceral, Vascular and Endocrine Surgery, University Hospital Halle (Saale) and Medical Faculty of the Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Straße 40, 06120, Halle (Saale), Germany. ulrich.ronellenfitsch@uk-halle.de.ORCID http://orcid.org/0000-0003-1107-813X
CovidSurg Collaborative

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring the COVID-19 pandemic, prioritization of COVID-19 patients led to delays in oncological surgery, potentially impacting patient outcomes. This analysis examines the effects of surgical delays in various tumor entities on resectability and postoperative mortality.

methodsData from the COVIDSurg Cancer Collaborative, an international prospective cohort study with 19,676 patients, collected between March 26, 2020, and September 16, 2020, were analyzed. Postoperative mortality and complete resection (R0) were the outcomes, with tumor entity, stage and delay to surgery as key exposures.

results17,486 patients underwent surgery during the study period, at a median time of three weeks after decision to operate (IQR = 4). 172 (1.0%) patients died within 30 days postoperatively. 15,143 (90.5%) patients had an R0 resection, 1352 (8.1%) an R1 resection and 230 (1.4%) had an R2 resection. Postoperative mortality was highest for oesophageal cancer (3.9%) and UICC stage IV (1.5%). For the overall population, there was no association between delay to surgery and resectability. There was an association between delay to surgery and postoperative mortality (p < 0.001), with the highest 30-day postoperative mortality observed for operations within two weeks following surgical decision.

conclusionTumor resectability and postoperative mortality in oncological surgeries are influenced by various factors. During the COVID-19 pandemic, moderate delays in surgeries were observed, with differences across tumor types, UICC stages and regions. While no tangible effects on resectability were found, postoperative mortality was higher after a shorter delay to surgery.

Indexed as

Cancer operationsCOVID-19 pandemicDelay to surgery

Identifiers

PMID42104020
PMCPMC13156375

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.