Evidence map›Paper›PMID 42103980›Full record

ReviewCurrent cardiology reports2026

Heart Disease in Older Women: Unique Challenges in Diagnosis and Management.

Radmila Lyubarova, Sarah Malik, Roopa Rao, Krishna K Patel, D Elizabeth Le, Nanette K Wenger, Annabelle Volgman, Carrie Puckett

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Radmila LyubarovaDepartment of Medicine/Cardiology, Albany Medical College, 43 New Scotland Ave, Albany, NY, US 12208, USA. lyubarr@amc.edu.
Sarah MalikDepartment of Medicine/Cardiology, Albany Medical College, 43 New Scotland Ave, Albany, NY, US 12208, USA.
Roopa RaoDepartment of Medicine/Cardiology, Indiana University Health, Indianapolis, IN, USA.
Krishna K PatelMount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
D Elizabeth LeSection of Cardiology, Portland VA Health Care System and Knight Cardiovascular Institute, Oregon Health & Sciences University, Portland, OR, USA.
Nanette K WengerEmory University School of Medicine, Atlanta, GA, USA.
Annabelle VolgmanRush Heart Center for Women, Rush University Medical Center, Chicago, IL, USA.
Carrie PuckettSection of Cardiology, Portland VA Health Care System and Knight Cardiovascular Institute, Oregon Health & Sciences University, Portland, OR, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis review examines the unique cardiovascular disease patterns in older women, focusing on sex and age-specific pathophysiology, diagnostic challenges, and disparities in management. We aim to clarify how aging and hormonal transitions influence disease presentation and outcomes among women, and to identify gaps in cardiovascular care. RECENT

findingsEmerging data demonstrate that older women are disproportionately affected by HFpEF, coronary microvascular dysfunction, atrial fibrillation, and valvular heart disease. These conditions are influenced by vascular stiffness, myocardial remodeling, and systemic inflammation and often present with atypical symptoms leading to diagnosis delays. Contemporary studies highlight persistent gaps in timely diagnosis, referral for advanced therapies, and representation in clinical trials. Increasing attention is being directed toward frailty, multimorbidity, and patient-centered care models in this population. Recognizing age and sex-specific characteristics, increasing representation of older women in clinical trials, improving equitable access to diagnostic and therapeutic resources, and aligning treatment decisions with patient priorities are critical to narrowing existing gaps and improving long-term outcomes for older women with cardiovascular disease.

Indexed as

AgingHeart DiseasesWomen's HealthAgedAge FactorsClinical Trials as TopicFemaleHealthcare DisparitiesHealth Services AccessibilityHumansPatient SelectionSex FactorsAgingCardiovascularHealth disparitiesHeart diseaseSex-specific differences

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.