Evidence map›Paper›PMID 42103946›Full record

ArticleNeuroradiology2026

Recanalizing distal and small medium vessel occlusions - single-center experience with the new Q catheters.

Michael Griessmair, Christian Maegerlein, Dominik Sepp, Dennis Martin Hedderich, Jannis Bodden, Silke Wunderlich, Claus Zimmer, Jan Kirschke, Maria Berndt-Mück, Martin Renz and 1 more

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Article in Neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Michael GriessmairDepartment of Neuroradiology, Technical University of Munich, Munich, Germany. michael.griessmair@tum.de.
Christian MaegerleinDepartment of Neuroradiology, Technical University of Munich, Munich, Germany.
Dominik SeppDepartment of Neuroradiology, Technical University of Munich, Munich, Germany.
Dennis Martin HedderichDepartment of Neuroradiology, Technical University of Munich, Munich, Germany.
Jannis BoddenDepartment of Neuroradiology, Technical University of Munich, Munich, Germany.
Silke WunderlichDepartment of Neurology, Technical University of Munich, Munich, Germany.
Claus ZimmerDepartment of Neuroradiology, Technical University of Munich, Munich, Germany.
Jan KirschkeDepartment of Neuroradiology, Technical University of Munich, Munich, Germany.
Maria Berndt-MückDepartment of Neuroradiology, Technical University of Munich, Munich, Germany.
Martin RenzDepartment of Neuroradiology, Technical University of Munich, Munich, Germany.
Tobias Boeckh-BehrensDepartment of Neuroradiology, Technical University of Munich, Munich, Germany. boeck-behrens@tum.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMechanical recanalization of distal and small medium vessel occlusions (DVOs and MeVOs) is technically challenging and likely associated with higher complication rates. Previous studies have shown promising results using Q aspiration catheters in MeVOs. We report our experience with Q catheters in an even more distal cohort of DVOs and small MeVOs, focusing on safety and efficacy.

methodsWe retrospectively reviewed our institutional stroke database for patients with DVOs or MeVOs treated using Q catheters. Baseline characteristics, technical outcomes including modified Thrombolysis in Cerebral Infarction (mTICI) score and modified first pass effect (mFPE), as well as clinical outcomes measured by the 90-day modified Rankin Scale (mRS) were analyzed. Outcomes were stratified by occlusion type and treatment technique. Periprocedural complications and their clinical impact were systematically assessed.

results57 occlusions in 47 patients were included. Mean age was 75.5 ± 12.7 years. Median National Institutes of Health Stroke Scale score was 7.7 ± 4.6 at admission and 4.9 ± 5.5 at discharge, while the rate of 90-day- mRS ≤ 2 was 37%. 39 were DVOs and 18 small MeVOs. Successful recanalization (mTICI ≥2b) was achieved in 75% overall, with lower rates in DVOs (71%) than MeVOs (83%). Stent retriever-assisted aspiration resulted in higher recanalization rates than aspiration alone (82% vs. 37%). mFPE was achieved in 42%. Periprocedural complications occurred in 9% of cases with no symptomatic intracranial hemorrhage (sICH) or PH2.

conclusionQ catheters appear to be safe and effective for DVOs and small MeVOs, achieving favorable recanalization rates with an acceptable complication profile. While the study is limited by its small sample size and retrospective design, these findings support the potential of Q catheters as a valuable tool in the treatment of distal and small vessel occlusions. Nevertheless, consistent to the recently published large distal trials, recanalization rates are lower, and complications occur more often in DVOs than in MeVOs, reflecting a different balance between the technical challenges and the smaller expected clinical benefit.

Indexed as

CathetersAgedAged, 80 and overCerebral AngiographyEquipment DesignFemaleHumansMaleRetrospective StudiesTreatment OutcomeDVO (distal vessel occlusion)MeVO (medium vessel occlusion)TICI (treatment in cerebral ischemia)

Identifiers

PMID42103946
PMCPMC13578080

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.