Evidence map›Paper›PMID 42103931›Full record

Trial reportScientific reports2026

Pathways between climate change and HIV health in rural Kenya: a qualitative analysis.

Tammy M Nicastro, Gladys Odhiambo, Stanley Jawuoro, Elly Weke, Elizabeth A Bukusi, Yihui A Yang, Helen A Harris-Fry, Suneetha Kadiyala, Sheri D Weiser

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02815579 (Agricultural Intervention for Food Security and HIV Health Outcomes in Kenya), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02815579 nacompletednot on this map

Agricultural Intervention for Food Security and HIV Health Outcomes in Kenya

TypeinterventionalSponsorUniversity of California, San FranciscoRan2016 to 2019Enrolled746ConditionsHIVArmsShamba Maisha Intervention
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tammy M NicastroDepartment of Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK. tammynicastro@gmail.com.
Gladys OdhiamboKenya Medical Research Institute, Nairobi, Kenya.
Stanley JawuoroKenya Medical Research Institute, Nairobi, Kenya.
Elly WekeKenya Medical Research Institute, Nairobi, Kenya.
Elizabeth A BukusiDepartment of Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Yihui A YangDepartment of Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Helen A Harris-FryDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, San Francisco, CA, USA.
Suneetha KadiyalaDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, San Francisco, CA, USA.
Sheri D WeiserDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Climate change-related severe weather events are heavily impacting regions with the highest prevalence of HIV, creating additional vulnerabilities for already vulnerable populations. Little is understood about how people perceive or experience the mechanisms by which extreme weather events affect the health of people living with HIV (PLHIV). We conducted a qualitative study using in-depth, semi-structured interviews with 40 PLHIV enrolled in a cluster randomized clinical trial that included 8 pairs of health facilities in rural Western Kenya, who were 18 years or older, receiving ART for > 6 months; had moderate to severe food insecurity; and practiced smallholder farming with access to surface water or aquifers. Intervention participants received a loan to purchase an irrigation pump and farming inputs and were provided climate-responsive, sustainable agriculture and financial literacy training. This study did not evaluate the impacts of the clinical trial. We aimed to understand participant perceptions of how climate change impacted their HIV health, and associated pathways for these impacts. Interviews were transcribed, translated, and double coded using an inductive-deductive-abductive thematic content approach. Almost all participants noted that droughts, flooding, and elevated temperatures had serious negative impacts on their health and wellbeing. Extreme weather negatively impacted their health via five key pathways, with the first being most prominent: (1) decreases in agricultural yields and income; (2) increased food insecurity and undernutrition; (3) medication non-adherence, missed clinic visits, and infrastructure erosion; (4) increased infections, and (5) displacement and forced migration. Several pathways were interrelated, with decreased agricultural yields and income being proximal to most other pathways. Participants perceived pathways by which severe weather negatively impacted their HIV health, and these pathways were bi-directional and reinforcing. Food and livelihood sources were devastated, and housing and infrastructure were negatively affected, causing a cascade of nutrition and health vulnerabilities. Understanding the contexts in which PLHIV are vulnerable to impacts of climate change will be essential to establish climate-responsive policies that can interrupt the pathways identified here. Cross-sector collaboration between the Kenyan Ministries of Agriculture and Health to develop climate-responsive policies to support PLHIV should be prioritized. The clinical trial start date was June 23, 2016. Trial Registration: Registered with ClinicalTrials.gov Identifier: NCT02815579.

Indexed as

Climate ChangeHIV InfectionsAdultAgricultureFemaleHumansKenyaMaleMiddle AgedQualitative ResearchRural PopulationAgricultureClimate changeHIVKenya

Identifiers

PMID42103931
PMCPMC13342556

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.