Evidence map›Paper›PMID 42103902›Full record

ArticleScientific reports2026

Trends and patterns of antimicrobial resistance among Staphylococcus aureus isolated from various clinical specimens: a national laboratory-based AMR surveillance, 2020-2024.

Zeleke Ayenew, Meseret Aseffa Oda, Semira Ebrahim Geleto, Tewodros Minwuyelet Anteneh, Etsehiwot Adamu Tsegaye, Yonas Mekonnen Gebeyehu, Dejenie Shiferaw Teklu, Degefu Beyene Gobena, Amete Mihret Teshale, Gebrie Alebachew Belete and 30 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors.

Zeleke AyenewEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia. zelekeayenew377@gmail.com.
Meseret Aseffa Oda *Ethiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Semira Ebrahim Geleto *Ethiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Tewodros Minwuyelet AntenehEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Etsehiwot Adamu TsegayeEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Yonas Mekonnen GebeyehuEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Dejenie Shiferaw TekluEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Degefu Beyene GobenaEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Amete Mihret TeshaleEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Gebrie Alebachew BeleteEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Surafel Fentaw DinkuEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Tesfa Addis KefaleEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Elias Seyoum DerebeEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Abera Abdeta KitabaEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Dawit Assefa WendifrawEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Ebisa FekedeEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Bruke Gezhagene BirhanuEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Mheret Tesfaye GobenaEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Addis AbebeEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Degefe HabteEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Senahara Korsa WakeEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Dawit Sekata DuressaEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Jemal Mohammed HussienEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Gemechis Bulti TuraEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Eshetu GadisaEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Dereje Mamuye GebretsadikEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Daniel Dejene WondimagegnehuEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Daniel Demissie GebremariamEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Birhan Moges EjiguEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Bethelhem Getu BekeleEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Estifanos TsigieEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Degu Ashagrie AlemuFelege Hiwot Comprehensive Specialized Hospital, Bahir Dar, Ethiopia.
Mezgebu Nega BizunehFelege Hiwot Comprehensive Specialized Hospital, Bahir Dar, Ethiopia.
Yesewbelay Minale NegesseFelege Hiwot Comprehensive Specialized Hospital, Bahir Dar, Ethiopia.
Rajiha Abubeker IbrahimEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Abebe Aseffa NegeriEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Getachew Tollera EtichaEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Gemechu Tadese LetaEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Negga Asamene AberaEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.
Eyasu Tigabu SeyoumEthiopian Public Health Institute, PO Box 1242, Addis Ababa, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is a global public health concern responsible for a wide range of infections. In Ethiopia, patterns and trends of MRSA in various clinical specimens are limited. Therefore, this study aimed to determine the trend and pattern of S. aureus isolated from 16 AMR surveillance sentinel sites. Laboratory-based AMR surveillance data from 2020 to 2024 was collected from various clinical specimens. Culture and antimicrobial susceptibility testing were performed using standard microbiology techniques. The data were analyzed using WHONET 2025 software version 25.15.5 and SPSS version 22. A total of 4,243 S. aureus isolates were analyzed in 16 AMR sentinel sites; most of them were from health facilities in Addis Ababa (46.6%). The trend of penicillin resistance among tested isolates showed persistently high (~ 90%) between 2020 and 2024. The trend of MRSA showed a noticeable slight decline from 37% in 2021 and 2022 to 30% in the 2024 period, and its overall prevalence was 32.2% (95% CI 30.3, 34.2). There has been a slight declining trend of MRSA since 2022 and fluctuating resistance rates in routinely tested antimicrobials. The susceptibility of isolates to last-resort antibiotics remains promising for treatment. The significant presence of MRSA in participating hospitals warrants continuous surveillance and strengthens the implementation of infection prevention and control measures.

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialMethicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsStaphylococcus aureusEthiopiaHumansMicrobial Sensitivity TestsPrevalenceAnti-Bacterial AgentsAMR surveillanceEthiopiaMRSAS. aureusSentinel siteTrend

Identifiers

PMID42103902
PMCPMC13346943

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.