Evidence map›Paper›PMID 42103775›Full record

ArticleNPJ vaccines2026

A BcfA-containing intranasal vaccine generated T

Alexa R Aubrey, Komal K Patel, Jesse M Hall, Mohamed M Shamseldin, Myra Guo, Gianni B DeLucia, Siddhi Shah, Kara N Corps, Rajendar Deora, Purnima Dubey

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alexa R Aubrey *Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH, USA.
Komal K Patel *Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH, USA.
Jesse M Hall *Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH, USA.
Mohamed M ShamseldinDepartment of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH, USA.
Myra GuoDepartment of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH, USA.
Gianni B DeLuciaDepartment of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH, USA.
Siddhi ShahDepartment of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH, USA.
Kara N CorpsCollege of Veterinary Biosciences, The Ohio State University, Columbus, OH, USA.
Rajendar DeoraDepartment of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH, USA.
Purnima DubeyDepartment of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH, USA. purnima.dubey@osumc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bordetella bronchiseptica (Bb) is a significant etiologic agent of respiratory disease in farm and companion animals. Current vaccines provide short-lived protection against disease, but do not elicit mucosal immunity that is critical for sustained protection. Here we tested a trivalent protein subunit vaccine composed of Bordetella antigens filamentous hemagglutinin (FHA) pertactin (Prn), and the dual antigen-adjuvant Bordetella colonization factor A (BcfA). Intranasal immunization of mice generated T

Identifiers

PMID42103775
PMCPMC13369460

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.