ArticleNature communications2026
Grid maps are disrupted after large-scale arena expansion and recover with experience.
Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Grid maps are disrupted after large-scale arena expansion and recover with experience.Nature communications · 2026Article
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3 authors.
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Abstract
The hexagonal firing pattern of grid cells in the medial entorhinal cortex (MEC) is thought to provide a universal spatial metric supporting vector-based navigation regardless of an environment's spatial scale. However, how the hexagonal pattern adapts to large changes in the spatial scale of an environment remains elusive. Using single-unit recordings in freely behaving male mice, we show that grid maps are substantially disrupted after large-scale but not medium-scale expansion of the recording arena. The disruption occurs when the scale ratio exceeds the scale ratio of successive grid cell modules, indicating that adaptation of grid cell representations within a module is constrained by a preconfigured spatial scale range of the module. Importantly, grid patterns recover gradually over multiple days of experience in the large-scale expanded arena. These findings challenge the notion of a universal spatial metric by grid cells, instead revealing a flexible system shaped by experience.
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