Evidence map›Paper›PMID 42102187›Full record

ArticleScience advances2026

Biogenesis and downstream effects of 3',5' and 2',3' cAMP isomers in plants.

Mingyue Li, Monika Chodasiewicz, Malavika Muraleedharan, Israel M Lopez, Michal Gorka, Olga Kerber, Saqer S Alotaibi, Andrew D L Nelson, Rene Lenobel, Jaroslava Friedecká and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mingyue LiInstitute of Science and Technology Austria (ISTA), 3400 Klosterneuburg (Austria).ORCID 0000-0003-0854-6924
Monika ChodasiewiczBiological and Environmental Science & Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.ORCID 0000-0002-0295-0638
Malavika MuraleedharanBiological and Environmental Science & Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
Israel M LopezBiological and Environmental Science & Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
Michal GorkaMax-Planck-Institute of Molecular Plant Physiology, 14476 Potsdam-Golm, Germany.
Olga KerberMax-Planck-Institute of Molecular Plant Physiology, 14476 Potsdam-Golm, Germany.
Saqer S AlotaibiDepartment of Biotechnology, College of Science, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.ORCID 0000-0002-6162-7953
Andrew D L NelsonThe Boyce Thompson Institute, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0001-9896-1739
Rene LenobelLaboratory of Growth Regulators, Faculty of Science, Palacký University and Institute of Experimental Botany of the Czech Academy of Sciences, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic.ORCID 0000-0001-7387-0056
Jaroslava FriedeckáLaboratory of Growth Regulators, Faculty of Science, Palacký University and Institute of Experimental Botany of the Czech Academy of Sciences, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic.ORCID 0000-0001-8030-6736
Aleksandra SkiryczMichigan State University, East Lansing, MI 48824, USA.ORCID 0000-0002-7627-7925
Jiří FrimlInstitute of Science and Technology Austria (ISTA), 3400 Klosterneuburg (Austria).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclic adenosine monophosphate (cAMP) is a fundamental second messenger involved in diverse signaling pathways across both animals and plants. While the role of 3',5'-cAMP has been extensively characterized, the biological significance of its structural isomer, 2',3'-cAMP, remains largely unexplored, particularly in plants. Here, we show that 2',3'-cAMP and 3',5'-cAMP represent parallel signaling systems in

Indexed as

ArabidopsisCyclic AMPAdenylyl CyclasesArabidopsis ProteinsGene Expression Regulation, PlantIsomerismMultiomicsProteomicsSignal TransductionAdenylyl CyclasesArabidopsis ProteinsCyclic AMP

Identifiers

PMID42102187
PMCPMC13155313

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.