ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2026
Mendosal suture patency beyond infancy: a large-scale computed tomography study in an Asian cohort.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeThe mendosal suture, or accessory occipital suture, is thought to obliterate prenatally or neonatally, and its persistence is often misinterpreted as a skull fracture. Although recent studies suggest that it may persist beyond infancy, its prevalence and clinical significance in Asian populations remain unclear. This study aimed to determine the prevalence and characteristics of persistent mendosal sutures in a Thai population aged 1-20 years.
methodsA retrospective review of 1403 cranial computed tomography scans was conducted, with three-dimensional reconstructions evaluated by three blinded investigators. Sutures were classified as completely patent (continuous horizontal line across lambdoid sutures) or partially patent (residual suture with areas of fusion), and intra- and interrater reliability were assessed using intraclass correlation coefficients.
resultsThe overall prevalence of persistent mendosal sutures was 6.4%, with partial patency (4.8%) more common than complete patency (1.6%); both were observed across all age groups. Intra- and interrater reliability was excellent. Median age differed statistically significantly among groups (P = 0.001): 16 years for partial patency, 8 years for complete patency, and 11 years for no suture. Cephalic index showed a small but statistically significant difference (P = 0.048), although all values remained within normal limits. No statistically significant associations were found with sex, family history of craniofacial anomalies, or other sutural synostoses.
conclusionThe mendosal suture persists into adulthood in 6.4% of Thais, challenging the assumption of consistent early-infancy obliteration. Its presence across all ages, lack of association with pathology, and normal cephalic indices suggest that it is a benign anatomical variant rather than a marker of disease.
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