Evidence map›Paper›PMID 42101532›Full record

ArticleDiscover oncology2026

Hematologic malignancies burden in China compared with the United States 1990-2021 and projections to 2040.

Wenshuai Zheng, Rui Qin, Hang Dong, Wentao Xiong, Xuan Zhou, Mingjuan Liu, Lixun Guan

Abstract read
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Article in Discover oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Wenshuai Zheng *Department of Hematology, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, China.
Rui Qin *Department of Hematology, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi, 445000, Hubei, China.
Hang Dong *Department of Neurosurgery, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, China.
Wentao XiongDepartment of Osteology, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, China.
Xuan ZhouDepartment of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, China. xuan081012@126.com.
Mingjuan LiuSenior Department of Hematology, Chinese PLA General Hospital, Beijing, China. llj0795@163.com.
Lixun GuanDepartment of Hematology, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, China. guanlixunhn@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHematologic malignancies, including leukemia, non-Hodgkin lymphoma (NHL), multiple myeloma (MM), and Hodgkin lymphoma (HL), represent some of the most prevalent cancers. This study aims to comprehensively analyze the epidemiological trends of these malignancies in China.

methodsUsing data from the Global Burden of Disease Study 2021 (GBD 2021), we conducted a detailed assessment of incidence cases, deaths, disability-adjusted life years (DALYs), and corresponding age-standardized rates (ASR) of hematologic malignancies in China. Additionally, we compared the disparity in disease burden between China and the United States (US).

resultsIn 2021, the incidence cases, deaths, and DALYs of all hematologic malignancies reached 238051.31, 117187.70, and 3894866.98, respectively, in China. From 1990 to 2021, although the age-standardized incidence rates (ASIR) of leukemia, MM, and NHL increased, the age-standardized death rates (ASDR) and age-standardized DALYs rates (ASDALYR) declined for all subtypes of hematologic malignancies, with the exception of MM. The ASIR of all subtypes of hematologic malignancies in the US was significantly higher than that in China, while the disparity of ASDALYR between the two countries was smaller. The ASRs for all subtypes of hematologic malignancies exhibited a positive correlation with age and were generally higher in males than in females. High body mass index (BMI) emerged as a significant risk factor contributing to deaths from all hematologic malignancies, and tobacco remains the leading contributor to leukemia-related deaths. Projections indicate that the burden of MM will continue to increase from 2022 to 2040.

conclusionsWhile the ASIR of hematologic malignancies has risen over recent decades, the ASDR and ASDALYR have showed a decreasing trend, reflecting China's efforts in reducing the burden of these diseases. However, the disparity in disease burden between China and the US underscores the substantial potential for improving the diagnosis, treatment, and care levels in China.

Indexed as

ChinaEpidemiologyHematologic malignanciesHodgkin lymphomaLeukemiaMultiple myelomaNon-Hodgkin lymphoma

Identifiers

PMID42101532
PMCPMC13323456

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