Evidence map›Paper›PMID 42101519›Full record

ArticleBrain structure & function2026

Internal connectivity of the mouse mesocortical ring and functional implications.

Luis Puelles, Elena Garcia-Calero

Abstract read
In one paragraph

Article in Brain structure & function, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Luis PuellesDepartamento de Anatomía Humana y Psicobiología, Facultad de Medicina, Universidad de Murcia, Campus de Ciencias de la Salud, Murcia, 30120, España.
Elena Garcia-CaleroDepartamento de Anatomía Humana y Psicobiología, Facultad de Medicina, Universidad de Murcia, Campus de Ciencias de la Salud, Murcia, 30120, España. ecalero@um.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mammalian mesocortex (MCx) was redefined recently as a complete ring intercalated between the allo- and iso-cortex, attending to the consistent expression of 46 selective gene markers. The MCx exhibits various other characteristics such as low myelin content of its fibers, a property directly related to its function and susceptibility to degenerative disorders. Irrespective of its shared molecular profile, the MCx ring differentiates into different sectors with singular molecular and cytoarchitectonic characteristics, such as the posterior orbitary cortex, the cingulate cortex, and the insula. In the present study, using anterograde connectivity experiments published in an Allen Institute for Brain Science public database ( https://brain-map.org/our-research/connectivity ), we analyzed the internal connectivity of the mesocortical ring. We observed that its different sectors are multiply interconnected, possibly achieving integrative functions. The medial posterior orbitary cortex stands out; it appears to play a higher hierarchical role within the MCx ring by sending and receiving projections from all mesocortical sectors.

Indexed as

Cerebral CortexNeural PathwaysAnimalsMaleMiceConnectomeLimbic systemPosterior orbitary cortexPsychopathySelf

Identifiers

PMID42101519
PMCPMC13156105

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.