ArticleArchives of microbiology2026
Unveiling the carbohydrate-active enzyme repertoire of Trichoderma caribbaeum IHBT through whole-genome analysis and transcriptional profiling.
Article in Archives of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Carbohydrate-active enzymes (CAZymes) play an important role in the efficient deconstruction of lignocellulosic biomass (LCB) and chitin, which is essential for sustainable bioenergy production and for the development of industrially important value-added products. Fungi, especially members of Trichoderma spp., are known as efficient degraders of biomass and represent valuable resources for expanding the known repertoire of CAZymes. This study presents the first report of the sequencing and annotation of a high-quality hybrid genome assembly of Trichoderma caribbaeum IHBT, isolated from the western Himalayan region, along with RNA-seq analysis to identify CAZyme-encoding genes potentially involved in the biomass degradation process. The assembled genome was 36.2 Mb in size, with a N50 value of 1.2 Mb and a GC content of 48%, indicating a high-quality genome assembly. Genome mining enabled the identification and functional annotation of 362 putative CAZyme-encoding genes. Time-course transcriptome profiling of T. caribbaeum IHBT grown on sugarcane bagasse (SB) revealed an upregulation of several genes involved in carbohydrate metabolism, including members of the glycoside hydrolase (GH; XP_013945330.1, UKZ69522.1, UKZ67968.1, XP_013947289.1, XP_013940790.1, and UKZ68144.1) and auxiliary activity (AA; UKZ70991.1, XP_013940326.1, XP_013944427.1, UKZ71564, and UKZ60083.1) families, including lytic polysaccharide monooxygenases (LPMOs). Weighted Gene Co-Expression Network Analysis (WGCNA) identified eight potential Hub genes, of which XP_013943413.1, XP_013940723.1, XP_013945605, and XP_013942713 are directly implicated in biomass deconstruction. Overall, the identified CAZyme-encoding genes offer significant potential for further functional characterization and application in biomass valorization, thereby supporting the development of sustainable circular economic strategies in prospective studies.
Indexed as
Identifiers
42101511What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.