Evidence map›Paper›PMID 42101291›Full record

ArticleInternational endodontic journal2026

Micro-CT Analysis of Solvent Use and Apical Enlargement in the Retreatment of S-Shaped Root Canals of Mandibular Molars.

Renata M S Leal, Maria C B P Campos, Felipe A Copelli, Lisa Y Oda, Clarissa T Rodrigues, Bruno C Cavenago, Emmanuel J N L Silva

Abstract read
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Article in International endodontic journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Renata M S LealDepartment of Restorative Dentistry, Federal University of Paraná, Curitiba, Paraná, Brazil.ORCID 0000-0002-8448-6671
Maria C B P CamposDepartment of Restorative Dentistry, Federal University of Paraná, Curitiba, Paraná, Brazil.
Felipe A CopelliDepartment of Restorative Dentistry, Federal University of Paraná, Curitiba, Paraná, Brazil.ORCID 0000-0002-7305-9519
Lisa Y OdaDepartment of Restorative Dentistry, Federal University of Paraná, Curitiba, Paraná, Brazil.ORCID 0000-0001-5203-5422
Clarissa T RodriguesDepartment of Restorative Dentistry, Federal University of Paraná, Curitiba, Paraná, Brazil.ORCID 0000-0002-9099-4242
Bruno C CavenagoDepartment of Restorative Dentistry, Federal University of Paraná, Curitiba, Paraná, Brazil.ORCID 0000-0003-3203-0899
Emmanuel J N L SilvaDepartment of Endodontics, School of Dentistry, Grande Rio University (UNIGRANRIO), Duque de Caxias, Rio de Janeiro, Brazil.ORCID 0000-0002-6445-8243

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 1CSRD VA 1
6 · The paper itself

Abstract

aimTo evaluate the endodontic retreatment of S-shaped mesial root canals of mandibular molars using the Reciproc Blue R25 and R40 instruments, with or without the use of an orange oil solvent, and to assess the effect of additional apical enlargement with the HyFlex EDM 50/0.03 instrument on root canal cleaning after retreatment. METHODOLOGY: Eighteen mesial root canals with double curvature from mandibular molars were prepared up to size 40/0.04 using HyFlex EDM instruments and obturated. Specimens were anatomically matched and allocated into two groups (n = 9) according to the retreatment protocol: Reciproc Blue R25 and R40 without solvent and Reciproc Blue R25 and R40 with orange oil solvent. Following filling removal, all canals underwent additional apical enlargement using the HyFlex EDM 50/0.03 instrument. Micro-computed tomographic scans were performed before and after obturation, after filling removal, and after apical enlargement. The percentage of remaining filling material, canal transportation, and centering ability were quantified by root canal thirds and in all root canal. Data were analysed using Student's t-test or Mann-Whitney U test for intergroup comparisons and paired Student's t-test or Wilcoxon signed-rank test for intragroup analyses (α = 0.05).

resultsNo significant differences were observed between retreatment protocols, regardless of the use of orange oil solvent, for any evaluated parameter (p > 0.05). Additional apical enlargement with the HyFlex EDM 50/0.03 instrument significantly reduced the overall volume of remaining filling material in both groups (p < 0.05). However, complete removal of the filling material was not achieved in any specimen. Apical enlargement did not result in significant changes in canal transportation or centering ability (p < 0.05).

conclusionThe use of an orange oil solvent did not improve filling material removal or influence canal shaping in S-shaped mesial root canals of mandibular molars. Additional apical enlargement with the HyFlex EDM 50/0.03 instrument enhanced root canal cleanliness without compromising canal anatomy, although residual filling material persisted.

Indexed as

Dental Pulp CavityMolarRoot Canal PreparationSolventsTooth ApexX-Ray MicrotomographyHumansPlant OilsRetreatmentRoot Canal Obturationorange oilPlant OilsSolventsendodonticsmicro‐CTroot canal retreatment

Identifiers

PMID42101291
PMCPMC13462376

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.