Evidence map›Paper›PMID 42101262›Full record

ArticleThe International journal of eating disorders2026

Daily Ovarian Hormone Exposure and Loss of Control Eating in Adolescent Girls: A Stage 2 Registered Report.

Tyler B Mason, Jeremy C Morales, Kathryn E Smith, Genevieve F Dunton, Raina D Pang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The International journal of eating disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tyler B MasonDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0001-7284-7890
Jeremy C MoralesDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0001-5458-031X
Kathryn E SmithDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0001-6555-0060
Genevieve F DuntonDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-4129-3829
Raina D PangDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-0216-1655

Funding

Daily Ovarian Hormone Exposure and Loss of Control Eating in Adolescent Girls: A Within-Day RDoC StudyR21MH126334 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MASON, TYLER, PANG, RAINA · 2022 to 2023
$454k
NIMH NIH HHS R21 MH126334NIMH NIH HHS R21MH126334
6 · The paper itself

Abstract

objectiveThis Stage 2 Registered Report examined (1) the main effects and interaction of within-person daily associations between ovarian hormones (i.e., estrogen, progesterone) and loss of control eating (LOCE), and (2) the within-person mediating roles of food-related reward anticipation and response inhibition.

methodsAdolescent girls (n = 43) with regular menstrual cycles completed a baseline session followed by 35 days of ecological momentary assessment (multiple times per day), go/no-go tasks measuring response inhibition (daily), and saliva samples for hormone analyses (daily).

resultsThere was a significant interaction between within-subjects estrogen and progesterone in relation to daily LOCE. Days when estrogen and progesterone were opposing (i.e., high estrogen, low progesterone and low estrogen, high progesterone) were associated with greater LOCE compared to days when both estrogen and progesterone were either high or low. Within-subjects, day-level progesterone level was negatively associated with higher reward anticipation, and greater prompt-level reward anticipation predicted higher subsequent LOCE at the following prompt; the indirect effect was non-significant, however. There were no associations of response inhibition with hormones or LOCE. DISCUSSION: Our findings highlight daily associations between ovarian hormones and LOCE among adolescent girls. Opposing levels of estrogen and progesterone heightened risk for LOCE. In addition, lower progesterone may increase food-related reward anticipation and in turn LOCE. Overall, this study advances momentary models of LOCE in adolescent girls by highlighting hormones and reward anticipation as maintenance processes for real-world LOCE.

Indexed as

EstrogensFeeding BehaviorInhibition, PsychologicalProgesteroneAdolescentAnticipation, PsychologicalEcological Momentary AssessmentFemaleHumansRewardSalivaEstrogensProgesteroneadolescentsbinge eatingecological momentary assessmentloss of controlovarian hormones

Identifiers

PMID42101262
PMCPMC13536244

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.