ArticleChemSusChem2026
Sustainable Syntheses of p-Hydroxycinnamic-Based Macrobisphenols: Progress, Challenges, and Comparative Assessment of Yield and Sustainability.
Article in ChemSusChem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Authors and funding
9 authors.
Funding
Abstract
Macrobisphenols are a family of bio-inspired bisphenols introduced in 2013, composed of two p-hydroxycinnamate units linked through ester bonds via a polyol scaffold. Unlike bisphenol A, macrobisphenols are non-endocrine-disrupting compounds, and display outstanding antiradical activity, making them attractive, safer alternatives for polymer-related applications. Their versatility enables use as plasticizers, antioxidants, and monomers for polymer and materials synthesis. Over the past 12 years, substantial progress has been made to enhance their industrial viability by expanding structural diversity through extensive libraries of analogs, significantly lowering production costs, and minimizing environmental impact through greener synthetic strategies. This article critically reviews the evolution of macrobisphenol synthesis, highlights recent advances in sustainable and scalable pathways, and provides practical guidelines for selecting the most cost-effective and environmentally responsible processes according to the targeted structure.
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Registered trials
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