Evidence map›Paper›PMID 42101011›Full record

ReviewChemical record (New York, N.Y.)2026

Unveiling the Role of Pseudomonas aeruginosa Quorum Sensing Inhibitors: The Road So Far.

Valeria Tudino, Sara Rossi, Leonardo Milioni, Chiara Cosenza, Gabriele Carullo, Sandra Gemma, Stefania Butini, Giuseppe Campiani

Abstract readReview
In one paragraph

Review in Chemical record (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Valeria TudinoDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
Sara RossiDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
Leonardo MilioniDepartment of Medical Biotechnologies, University of Siena, Siena, Italy.
Chiara CosenzaDepartment of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
Gabriele CarulloDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.ORCID 0000-0002-1619-3295
Sandra GemmaDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.ORCID 0000-0002-8313-2417
Stefania ButiniDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
Giuseppe CampianiDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ESKAPE bacteria represent a global threat to public health. These microorganisms employ a type of cell-cell communicationnamed "quorum sensing (QS) system," which involves the activation of specific signals to modulate drug resistance and pathogenic behaviors. Noteworthy, resistance of Pseudomonas aeruginosa to antibiotics is increasing, thus leading to a greater interest in the development of new antibacterial compounds by exploring valuable targets such as its complex QS system. This review intends to provide an extensive report about the advances in the identification of promising P. aeruginosa QS inhibitors as potential novel therapeutic options. This work represents a comprehensive analysis of research articles available on Pubmed, Scopus, and Google Scholar, from January 2020 to July 2025, referring to promising antivirulence compounds, affecting P. aeruginosa QS system.

Indexed as

Anti-Bacterial AgentsPseudomonas aeruginosaQuorum SensingBacterial ProteinsHumansVirulence FactorsAnti-Bacterial AgentsBacterial ProteinsVirulence Factorsantimicrobial resistanceESKAPE pathogensPseudomonas aeruginosaquorum sensingvirulence factors

Identifiers

PMID42101011
PMCPMC13387964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.