Evidence map›Paper›PMID 42100910›Full record

ArticleJournal of global health2026

The association between the diabetes mellitus duration and the risk of pulmonary tuberculosis in the elderly: evidence from a community-based study in China.

Yijun He, Yan Qian, Henan Xin, Jiang Du, Xuefang Cao, Juanjuan Huang, Lingyu Shen, Yuanzhi Di, Yaqi Zhao, Zihan Li and 5 more

Abstract read
In one paragraph

Article in Journal of global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yijun He *NHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yan Qian *Longyou County People's Hospital, Zhejiang, China.
Henan XinNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jiang DuNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Xuefang CaoNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Juanjuan HuangNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Lingyu ShenNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yuanzhi DiNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yaqi ZhaoNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zihan LiNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Boxuan FengNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jianguo LiangNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Qi JinNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Ping ZhuCenter for Diseases Control and Prevention of Quzhou, Zhejiang, China.
Lei GaoNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diabetes mellitus (DM) is one of the risk factors for pulmonary tuberculosis (TB) development, and the dual burden of these diseases poses a significant public health challenge. However, the impact of DM duration on the risk of pulmonary TB, which is crucial for developing precise intervention strategies, has not been clarified. Methods: We conducted a retrospective study based on an active case-finding project on pulmonary TB in Quzhou City, Zhejiang Province, in 2022, to explore the association between DM duration and the risk of pulmonary TB among elderly individuals aged ≥65 years. We followed participants from the 2022 baseline screening until the date of pulmonary TB diagnosis, death, or 31 December 2024, whichever came first. Results: Among the 212 616 participants with a median age of 72 (interquartile range = 68-76) years, 724 cases with pulmonary TB were reported during the follow-up of 521 173.131 person-years, with an incidence of 138.917/100 000 person-years in 2022-2024. Participants with DM had a significantly higher risk of developing pulmonary TB compared with those without DM (adjusted sub-distribution hazard ratio (aSDHR) = 1.353; 95% confidence interval (CI) = 1.062-1.724). Notably, participants with a DM duration of 2-5 years had a significantly higher risk of pulmonary TB (aSDHR = 2.125; 95% CI = 1.481-3.047), with no other DM duration groups showing significant associations. Conclusions: We found DM to be a risk factor for the development of pulmonary TB, with a particularly pronounced effect in the subgroup with a disease duration of 2-5 years. Further research is needed to verify this association, elucidate its underlying pathophysiological mechanisms, and conduct targeted cost-benefit analyses to provide a basis for public health decision-making.

Indexed as

Diabetes MellitusTuberculosis, PulmonaryAgedChinaFemaleHumansIncidenceMaleRetrospective StudiesRisk FactorsTime Factors

Identifiers

PMID42100910
PMCPMC13154338

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.