Evidence map›Paper›PMID 42100858›Full record

ArticleJournal of the American Chemical Society2026

Outer Membrane-Peptidoglycan Anchoring in

Amr M El-Araby, Uxía Pérez de José, Vega Miguel-Ruano, Mijoon Lee, Rhona Feltzer, Luis F Avila-Cobian, Dusan Hesek, Jed F Fisher, Juan A Hermoso, Shahriar Mobashery

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amr M El-ArabyDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Uxía Pérez de JoséDepartment of Crystallography and Structural Biology, Instituto de Química-Física "Blas Cabrera", Consejo Superior de Investigaciones Científicas, Madrid 28006, Spain.
Vega Miguel-RuanoDepartment of Crystallography and Structural Biology, Instituto de Química-Física "Blas Cabrera", Consejo Superior de Investigaciones Científicas, Madrid 28006, Spain.
Mijoon LeeDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.ORCID 0000-0001-7432-0427
Rhona FeltzerDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Luis F Avila-CobianDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.ORCID 0000-0002-1292-1611
Dusan HesekDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.ORCID 0000-0001-6288-8824
Jed F FisherDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Juan A HermosoDepartment of Crystallography and Structural Biology, Instituto de Química-Física "Blas Cabrera", Consejo Superior de Investigaciones Científicas, Madrid 28006, Spain.
Shahriar MobasheryDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.ORCID 0000-0002-7695-7883

Funding

Chemistry-Biochemistry-Biology Interface (CBBI) Program at Notre DameT32GM145773 · NIGMS · UNIVERSITY OF NOTRE DAME · PI Christian Corey Melander · 2022 to 2026
$1.5M
Targeting Gram-Negative Bacteria for Antibacterial StrategiesR35GM158092 · NIGMS · UNIVERSITY OF NOTRE DAME · PI Shahriar Mobashery · 2025 to 2026
$829k
NIGMS NIH HHS R35 GM158092NIGMS NIH HHS T32 GM145773
6 · The paper itself

Abstract

Gram-negative bacteria have an elaborate envelope that is composed of an outer membrane, the cell wall, and the inner membrane, which collectively encase the cytoplasm. The outer membrane is covalently anchored to the peptidoglycan, the major constituent of the cell wall. We document that the gene product of PA2854 is the catalyst that performs this transformation between the cell wall and the outer-membrane lipoprotein OprI in live

Indexed as

Bacterial Outer Membrane ProteinsPeptidoglycanPseudomonas aeruginosaCrystallography, X-RayModels, MolecularBacterial Outer Membrane ProteinsPeptidoglycan

Identifiers

PMID42100858
PMCPMC13401754

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.