ArticleFrontiers in microbiology2026
Composition and diversity of gut microbiota in non-erosive reflux disease.
Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
Objective: Non-erosive reflux disease (NERD) is a prevalent gastrointestinal disorder with complex pathophysiology. Recent evidence suggests a potential role of gut microbiota in its development. This study aimed to characterize the gut microbiota in patients with NERD, and to explore microbial biomarkers for disease differentiation. Methods: We enrolled 40 patients with NERD, along with 18 healthy controls (HCs). Fecal samples were collected and analyzed using 16S ribosomal RNA (rRNA) gene sequencing. Gut microbial diversity and composition, linear discriminant analysis effect size (LEfSe), and receiver operating characteristic (ROC) curves were evaluated. Results: The microbial structure and composition of NERD patients were distinct from those of HCs. Alpha diversity was significantly lower in NERD patients than in controls ( Conclusion: This study identified microbiota dysbiosis of gut microbiota in NERD patients.
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