Evidence map›Paper›PMID 42100668›Full record

ArticleResuscitation plus2026

Neural regions associated with memories of Recalled Experiences of Death (REDs; authentic Near‑Death Experiences [NDEs]): a preliminary functional MRI study.

José Alonso Ruiz, Mayte Rodríguez-González-Moro, Tomás Segura, Víctor M Serrano Del Pueblo, Salvador D Aznar-Cervantes

Abstract read
In one paragraph

Article in Resuscitation plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

José Alonso RuizFaculty of Medicine, Catholic University of Murcia (UCAM), 30107 Murcia, Spain.
Mayte Rodríguez-González-MoroFaculty of Nursing, Catholic University of Murcia (UCAM), 30107 Murcia, Spain.
Tomás SeguraFaculty of Medicine, University of Castilla-La Mancha, 02008 Albacete, Spain.
Víctor M Serrano Del PuebloFaculty of Medicine, University of Castilla-La Mancha, 02008 Albacete, Spain.
Salvador D Aznar-CervantesBiotechnology Research Group, Murcian Institute for Agricultural and Environmental Research and Development, 30150 Murcia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This observational study examined brain activation patterns when people relive their memories of recalled experiences of death (REDs), also known as authentic near-death experience (NDE) memories, using structural and functional MRI under normal cerebral perfusion in participants with clinically documented life-threatening events and loss of consciousness. Methods: Fifteen participants (7 women, 8 men; aged 18-75) were evaluated using two scanners. A block-design paradigm (recall RED-rest) was applied, with prior psychological training, physiological monitoring, and radiological review. Analysis was performed using SPM25. A whole-brain threshold was applied at an uncorrected level of Results: Significant activations were observed in the precuneus (BA7), posterior cingulate cortex (BA23/31), medial prefrontal cortex (BA10), dorsolateral prefrontal cortex (BA9/46), angular gyrus (BA39), secondary visual cortex (BA18/19), middle temporal gyrus (BA21), and orbitofrontal cortex (BA47). The parahippocampal region (BA36) showed a non-significant trend. No activation was found in primary sensorimotor or limbic areas. Discussion: The reliving of RED/authentic NDE memories was associated with the engagement of brain networks implicated in autobiographical memory and the default mode network (DMN), suggesting the involvement of introspective and self-referential processes. The observed activation patterns were not consistent with those typically reported for primary sensory hallucinations. Conclusions: Controlled reliving of memories of REDs/authentic NDEs may represent a useful experimental paradigm for investigating multisensory autobiographical memory and neural processes related to conscious self-experience. These findings are consistent with vivid episodic recollection and differ from neural patterns commonly associated with imagined or false memories.

Indexed as

Autobiographical memoryBlood Oxygen Level Dependent (BOLD)Functional Magnetic Resonance Imaging (fMRI)Near-Death Experience (NDE)NeuroimagingRecalled Experience of Death (RED)

Identifiers

PMID42100668
PMCPMC13147998

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.