Evidence map›Paper›PMID 42100660›Full record

ArticleFrontiers in cellular and infection microbiology2026

Establishment of tentative epidemiological cutoff values of faropenem against Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Haemophilus influenzae, and Streptococcus pneumoniae.

Shi Wu, Yang Yang, Dandan Yin, Feng Xue, Yun Li, Wei Kang, Qiwen Yang, Jie Lin, Yunsong Yu, Demei Zhu and 2 more

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In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shi WuInstitute of Antibiotics, Huashan Hospital, Fudan University, and Key Laboratory of Clinical Pharmacology of Antibiotics, Shanghai, China.
Yang YangInstitute of Antibiotics, Huashan Hospital, Fudan University, and Key Laboratory of Clinical Pharmacology of Antibiotics, Shanghai, China.
Dandan YinInstitute of Antibiotics, Huashan Hospital, Fudan University, and Key Laboratory of Clinical Pharmacology of Antibiotics, Shanghai, China.
Feng XueDepartment of Laboratory Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Yun LiDepartment of Laboratory Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Wei KangInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China.
Qiwen YangInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China.
Jie LinDepartment of Laboratory Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Yunsong YuDepartment of Laboratory Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Demei ZhuInstitute of Antibiotics, Huashan Hospital, Fudan University, and Key Laboratory of Clinical Pharmacology of Antibiotics, Shanghai, China.
Yan GuoInstitute of Antibiotics, Huashan Hospital, Fudan University, and Key Laboratory of Clinical Pharmacology of Antibiotics, Shanghai, China.
Fupin HuInstitute of Antibiotics, Huashan Hospital, Fudan University, and Key Laboratory of Clinical Pharmacology of Antibiotics, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to establish tentative epidemiological cutoff values (TECOFFs) for faropenem against Methods: A total of 2,032 bacterial isolates were collected from Peking University First Hospital, Peking Union Medical College Hospital, Huashan Hospital affiliated with Fudan University, and Sir Run Run Shaw Hospital affiliated with Zhejiang University School of Medicine between 2019 and 2021. The susceptibility of these bacteria to faropenem was determined using the broth microdilution and disk diffusion methods in the clinical microbiology laboratories of these four hospitals. To establish wild-type TECOFFs for faropenem, isolates susceptible to ertapenem for Results: The MIC TECOFF for faropenem against Conclusion: The TECOFFs for faropenem against the tested bacteria were established. These data are useful for clinical microbiologists and clinicians in the interpretation of the results of faropenem susceptibility testing.

Indexed as

Anti-Bacterial Agentsbeta-LactamsEscherichia coliHaemophilus influenzaeKlebsiella pneumoniaeStaphylococcus aureusStreptococcus pneumoniaeHumansMicrobial Sensitivity TestsAnti-Bacterial Agentsbeta-Lactamsfropenemantimicrobial susceptibility testingepidemiological cut-off valuesEscherichia colifaropenemHaemophilus influenzaeKlebsiella pneumoniaeStaphylococcus aureusStreptococcus pneumoniae

Identifiers

PMID42100660
PMCPMC13143937

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