ArticleInternational journal of women's health2026
The Serum Platelet-Albumin Ratio in Hyperemesis Gravidarum: A Retrospective Comparative Study.
Article in International journal of women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: This study aimed to evaluate the association between platelet-to-albumin ratio (PAR) and hyperemesis gravidarum (HG), and to assess its potential diagnostic value. Patients and Methods: This retrospective comparative study was conducted at a tertiary obstetrics center between January 2024 and December 2025. A total of 160 pregnant women were included (80 with HG and 80 healthy controls). Demographic, clinical, and laboratory parameters were analyzed. Results: Gravidity and parity differed significantly between groups (p<0.001). Among laboratory parameters, TSH (1.64±0.53 vs 1.20±0.39, p=0.006), potassium (4.06±0.41 vs 3.95±0.43, p=0.003), albumin (42.69±5.72 vs 39.59±8.56, p<0.001), and PAR (6.15±1.49 vs 9.26±2.89, p<0.001) were significantly different. ROC analysis demonstrated that PAR had a cut-off value of ≥6.51 for predicting HG (AUC = 0.825, 95% CI: 0.74-0.88), with 82.1% sensitivity and 66.2% specificity. The positive predictive value (PPV) was 80.9% and the negative predictive value (NPV) was 79.1%. Conclusion: PAR levels were significantly elevated in patients with HG and may serve as a simple and accessible biomarker. However, larger prospective studies are required to validate these findings.
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