Evidence map›Paper›PMID 42100455›Full record

ArticleRSC advances2026

Synthesis of condensed chiral pyranopyran derivatives with antiproliferative activity using domino Knoevenagel-IMHDA sequences.

Sándor Balázs Király, Balázs Buglyó, Otieno Michael Ooko, Attila Bényei, Erika Lisztes, Balázs István Tóth, Tamás Bíró, Kristóf Borozsnyai, Dávid Oláh, Gábor Vasvári and 4 more

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sándor Balázs KirályDepartment of Organic Chemistry, University of Debrecen P. O. Box 400 4002 Debrecen Hungary kiraly.sandor.balazs@science.unideb.hu kurtan.tibor@science.unideb.hu.ORCID https://orcid.org/0000-0003-2440-1493
Balázs BuglyóDepartment of Organic Chemistry, University of Debrecen P. O. Box 400 4002 Debrecen Hungary kiraly.sandor.balazs@science.unideb.hu kurtan.tibor@science.unideb.hu.
Otieno Michael OokoDepartment of Organic Chemistry, University of Debrecen P. O. Box 400 4002 Debrecen Hungary kiraly.sandor.balazs@science.unideb.hu kurtan.tibor@science.unideb.hu.
Attila BényeiDepartment of Physical Chemistry, University of Debrecen Egyetem Square 1 4032 Debrecen Hungary.ORCID https://orcid.org/0000-0002-0617-6264
Erika LisztesDepartment of Physiology, University of Debrecen Nagyerdei krt. 98. 4032 Debrecen Hungary.
Balázs István TóthDepartment of Physiology, University of Debrecen Nagyerdei krt. 98. 4032 Debrecen Hungary.
Tamás BíróDepartment of Immunology, University of Debrecen Egyetem Square 1 4032 Debrecen Hungary.
Kristóf BorozsnyaiDepartment of Organic Chemistry, University of Debrecen P. O. Box 400 4002 Debrecen Hungary kiraly.sandor.balazs@science.unideb.hu kurtan.tibor@science.unideb.hu.
Dávid OláhDepartment of Organic Chemistry, University of Debrecen P. O. Box 400 4002 Debrecen Hungary kiraly.sandor.balazs@science.unideb.hu kurtan.tibor@science.unideb.hu.
Gábor VasváriDepartment of Pharmaceutical Technology, University of Debrecen Rex Ferenc Street 1 4002 Debrecen Hungary.
Dániel NemesDepartment of Pharmaceutical Technology, University of Debrecen Rex Ferenc Street 1 4002 Debrecen Hungary.ORCID https://orcid.org/0000-0002-5477-0540
Miklós VecsernyésDepartment of Pharmaceutical Surveillance and Economics, University of Debrecen Rex Ferenc Street 1 4002 Debrecen Hungary.
Ferenc FenyvesiDepartment of Molecular and Nanopharmaceutics, University of Debrecen Rex Ferenc Street 1 4002 Debrecen Hungary.
Tibor KurtánDepartment of Organic Chemistry, University of Debrecen P. O. Box 400 4002 Debrecen Hungary kiraly.sandor.balazs@science.unideb.hu kurtan.tibor@science.unideb.hu.ORCID https://orcid.org/0000-0002-8831-8499

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We explored a domino Knoevenagel-intramolecular hetero-Diels-Alder (IMHDA) sequence, in which chiral pentaheterocyclic frameworks containing a pyrano[4,3-

Identifiers

PMID42100455
PMCPMC13146377

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.