Evidence map›Paper›PMID 42100439›Full record

ArticleCase reports in infectious diseases2026

Primary Pleural Tuberculosis Presenting With Noncaseating Granulomas: A Diagnostic Challenge.

Maria Akiki, Chebly Dagher, Jessica Abrantes-Figueiredo

Abstract read
In one paragraph

Article in Case reports in infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maria AkikiDepartment of Internal Medicine, University of Connecticut, Farmington, 06030, Connecticut, USA, uconn.edu.ORCID https://orcid.org/0009-0000-8204-8304
Chebly DagherDepartment of Internal Medicine, University of Connecticut, Farmington, 06030, Connecticut, USA, uconn.edu.ORCID https://orcid.org/0009-0003-2377-7859
Jessica Abrantes-FigueiredoDivision of Infectious Diseases, Saint Francis Hospital and Medical Center, Hartford, 06105, Connecticut, USA, stfranciscare.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculous pleural effusion is the second most common form of extrapulmonary tuberculosis after tuberculous lymphadenitis. Despite its frequency, diagnosis remains challenging due to its paucibacillary nature, and confirmation often requires invasive procedures. We report a 26-year-old male with no significant medical history who presented with persistent dyspnea, cough, and left-sided chest pain after recent travel to Pakistan. He denied known tuberculosis exposure. Imaging demonstrated a left pleural effusion, and thoracentesis revealed a lymphocytic exudate with elevated adenosine deaminase. Pleural fluid acid-fast bacilli smear and tuberculosis polymerase chain reaction were negative. Given the high clinical suspicion for tuberculosis, the patient underwent thoracoscopy with pleural biopsy, which demonstrated noncaseating granulomas. Although the histopathological findings were atypical, empiric antituberculous therapy was initiated. One month later, pleural biopsy cultures grew

Indexed as

Mycobacterium tuberculosisnoncaseating granulomapleural biopsypleural tuberculosisthoracoscopy

Identifiers

PMID42100439
PMCPMC13147350

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.