Evidence map›Paper›PMID 42100376›Full record

ArticleLife medicine2026

Salivary volatilome profiling in pediatric eosinophilic esophagitis: a pilot study on a non-invasive approach in clinical practice.

Rosamaria Capuano, Carla Petrella, Christian Barbato, Giulia D'Arcangelo, Giusy Russo, Alexandro Catini, Antonio Minni, Corrado Di Natale, Salvatore Oliva

Abstract read
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In one paragraph

Article in Life medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rosamaria CapuanoDepartment of Electronic Engineering, and Interdepartmental Centre for Volatilomics "A. D'Amico", University of Rome Tor Vergata, Rome 00133, Italy.
Carla PetrellaInstitute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Sapienza University of Rome, Rome 00161, Italy.
Christian BarbatoInstitute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Sapienza University of Rome, Rome 00161, Italy.
Giulia D'ArcangeloPediatric Gastroenterology and Liver Unit, Maternal and Child Health Department, Sapienza University of Rome, Rome 00161, Italy.
Giusy RussoPediatric Gastroenterology and Liver Unit, Maternal and Child Health Department, Sapienza University of Rome, Rome 00161, Italy.
Alexandro CatiniDepartment of Electronic Engineering, and Interdepartmental Centre for Volatilomics "A. D'Amico", University of Rome Tor Vergata, Rome 00133, Italy.
Antonio MinniDepartment of Sensory Organs, Sapienza University of Rome, Rome 00161, Italy.
Corrado Di NataleDepartment of Electronic Engineering, and Interdepartmental Centre for Volatilomics "A. D'Amico", University of Rome Tor Vergata, Rome 00133, Italy.
Salvatore OlivaPediatric Gastroenterology and Liver Unit, Maternal and Child Health Department, Sapienza University of Rome, Rome 00161, Italy.ORCID https://orcid.org/0000-0003-2348-2308

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophilic esophagitis (EoE) is a chronic immune disease requiring repeated endoscopies for diagnosis and monitoring in children. Saliva represents a promising non-invasive biofluid, and volatile organic compounds (VOCs) may indicate disease presence and activity. This study aimed to examine the VOCs profile in saliva samples from children with EoE and to compare it with other gastrointestinal (GI) conditions and healthy controls. Thirty-five samples from children with EoE (including 13 active and 22 non-active cases), 19 from children with other GI conditions, and 46 from healthy controls were analyzed. Gas chromatography-ion mobility spectrometry (GC-IMS) identified 63 distinct VOC signal areas. The abundance of 16 of them was found significantly different (

Indexed as

childreneosinophilic esophagitisnon-invasive monitoringsalivavolatile organic compounds

Identifiers

PMID42100376
PMCPMC13148378

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.