ReviewSage open pediatrics
Clinical Characteristics, Management, and Prognosis of Newborns with Aplasia Cutis Congenita Type I: A Systematic Review and Case Report.
Review in Sage open pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To synthesize the clinical characteristics, management, and outcomes of newborns with aplasia cutis congenita (ACC) type I. Introduction: ACC type I is a rare congenital condition characterized by isolated scalp defects without associated malformations. Evidence is limited and fragmented. Methods: We conducted a systematic review of studies reporting individual-level clinical data, including case reports, case series, and correspondence describing individual patients, following PRISMA guidelines. An additional clinical case was included. Results: Thirty-six studies, including 69 newborns, were analyzed. Most lesions were solitary (84.1%), located on the vertex (61.9%), superficial (55%), and more frequent in males (60.9%). Management was predominantly surgical. Complications were uncommon (21.3%), and outcomes were generally favorable. Conclusion: ACC type I typically presents as an isolated scalp defect with a favorable prognosis. Lesion characteristics and risk of complications should guide management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.