ArticleFrontiers in medicine2026
Association of endoscopic intervention with mortality in gastrointestinal bleeding after open-heart surgery: a propensity-score cohort study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Postoperative gastrointestinal bleeding (GIB) after open-heart surgery is associated with increased mortality, yet the prognostic impact of endoscopic intervention remains uncertain. Methods: We conducted a single-center retrospective cohort study of adults who developed GIB within 30 days after open-heart surgery (2017-2024). Patients were categorized into endoscopy and non-endoscopy groups, and propensity-score full matching was used to balance baseline covariates. The primary outcome was 30-day all-cause mortality; secondary outcomes were 1-year all-cause mortality, major postbleeding in-hospital complications (including acute myocardial infarction, acute respiratory distress syndrome, and other serious postoperative events), and postbleeding hospital length of stay. Results: Of 712 patients screened, 271 were included (endoscopy Discussion: Among clinically eligible patients with postoperative GIB after open-heart surgery, lower 30-day and 1-year mortality rates were observed in those undergoing endoscopic intervention, whereas no statistically significant differences were observed in major postbleeding in-hospital complications or hospital length of stay. Given the retrospective nature of the study, these results should be considered hypothesis-generating rather than confirmatory, serving as a basis for future prospective investigations.
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