Evidence map›Paper›PMID 42100191›Full record

ArticleFrontiers in endocrinology2026

Prolactin, cortisol, and extracellular osmolality regulate

Jason P Breves, Ming-Wen Hu, Mayu Inokuchi, Lucia A Seale, Andre P Seale

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jason P BrevesDepartment of Biology, Skidmore College, Saratoga Springs, NY, United States.
Ming-Wen HuDepartment of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Mayu InokuchiDepartment of Aquatic Bioscience, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo, Tokyo, Japan.
Lucia A SealePacific Biosciences Research Center, University of Hawai'i at Mānoa, Honolulu, HI, United States.
Andre P SealeDepartment of Human Nutrition, Food, and Animal Sciences, University of Hawai'i at Mānoa, Honolulu, HI, United States.

Funding

Selenium metabolism in cold-induced adaptive thermogenesisR01DK128390 · NIDDK · UNIVERSITY OF HAWAII AT MANOA · PI SEALE, LUCIA ANDREIA · 2021 to 2025
$2.0M
NIDDK NIH HHS R01 DK128390
6 · The paper itself

Abstract

Objective: Euryhaline fishes can inhabit salinities ranging from fresh water (FW) to seawater (SW), in part because their endocrine system aligns the ion-transporting capacities of branchial ionocytes with the external environment. Ionocytes also directly sense extracellular osmolality and adjust their functions accordingly; therefore, this study investigated the interplay between osmotic conditions and osmoregulatory hormones in Mozambique tilapia ( Methods: We first combined hypophysectomy, hormone replacement, RNA-Seq, and qPCR to identify Results: Our findings indicate that 1) Prl's capacity to antagonize cortisol-stimulated Conclusions: The combined actions of osmotic stimuli, Prl, and cortisol shape the branchial expression of

Indexed as

Cystic Fibrosis Transmembrane Conductance RegulatorFish ProteinsHydrocortisoneImmediate-Early ProteinsProlactinProtein Serine-Threonine KinasesTilapiaTranscription FactorsAnimalsGene Expression RegulationGillsOsmolar ConcentrationOsmoregulationSalinitySerum-Glucocorticoid Regulated KinasesCystic Fibrosis Transmembrane Conductance RegulatorFish ProteinsHydrocortisoneImmediate-Early ProteinsProlactinProtein Serine-Threonine KinasesSerum-Glucocorticoid Regulated KinasesTranscription Factorseuryhalinefishgillhormoneion transporterosmoregulationRNA-Seqsalinity

Identifiers

PMID42100191
PMCPMC13143792

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.