Evidence map›Paper›PMID 42100167›Full record

ArticleInnovation in aging2026

Trajectories of social health, cognitive, and daily functioning in community-dwelling older adults.

Anna Marseglia, Eline Verspoor, Marieke Perry, Myrra Vernooij-Dassen, Jeannie-Marie S Leoutsakos, Henry Brodaty, Jean Stafford, Mohammad Arfan Ikram, Joanna Rymaszewska, Anna-Karin Welmer and 5 more

Abstract read
In one paragraph

Article in Innovation in aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Anna MarsegliaDivision of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences, and Society, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-9672-6978
Eline VerspoorDepartment of Geriatrics, Radboudumc Alzheimer Center, Radboud University Medical Center, Nijmegen, The Netherlands.
Marieke PerryDepartment of Geriatrics, Radboudumc Alzheimer Center, Radboud University Medical Center, Nijmegen, The Netherlands.
Myrra Vernooij-DassenDepartment IQ Health, Radboud University Medical Center, Nijmegen, The Netherlands.
Jeannie-Marie S LeoutsakosDivision of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Henry BrodatyCentre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0001-9487-6617
Jean StaffordMRC Unit for Lifelong Health and Ageing at UCL, Faculty of Population Health Sciences, University College London, London, United Kingdom.
Mohammad Arfan IkramDepartment of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0003-0372-8585
Joanna RymaszewskaDepartment of Clinical Neuroscience, Faculty of Medicine, Wroclaw University of Science and Technology, Wrocław, Poland.
Anna-Karin WelmerAging Research Center, Department of Neurobiology, Care Sciences, and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-5819-8724
Karin Wolf-OstermannInstitute for Public Health and Nursing Research (IPP), University of Bremen, Bremen, Germany.
Frank J WoltersDepartment of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Amaia Calderón-LarrañagaAging Research Center, Department of Neurobiology, Care Sciences, and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-9064-9222
René J F MelisDepartment of Geriatrics, Radboudumc Alzheimer Center, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0002-7863-4738
SHARED Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Cognitive and functional impairments can both influence and result from deteriorating social health (SH), yet their interplay during aging remains poorly understood. This study investigated the concordance and discordance of trajectories in SH, cognitive, and daily functioning. Research Design and Methods: We analyzed 15-year follow-up data (2001-2015) from 2,848 initially dementia-free older adults in the Swedish National study on Aging and Care in Kungsholmen. Cognition and daily functioning were assessed with the Mini-Mental State Examination and activities of daily living (ADLs)/instrumental ADLs. SH encompassed indices of social participation, connections, and support. Trajectories across these five dimensions were identified using latent growth curve analyses, latent class growth analyses, and growth mixture models. Results: Two cognitive trajectories-relatively preserved (91%) and fast decline (9%)-and two daily functioning trajectories-stable (95%) and declining (5%)-were identified. SH trajectories included stable groups, gradually declining social participation (70%), and low initial social connections (29%). Social support showed stable (95%), declining (2%), and increasing (3%) trajectories. Women were more likely to belong to the initially low-stable social connections group, whereas higher education was linked to favorable trajectories across most dimensions but not social support. Concordance was observed among those with the lowest cognitive, daily functioning, and SH profiles. Notably, increasing social support was linked to low cognition but high daily functioning (odds ratios [OR] = 4.2, 95% CI: 2.3, 7.6). Discussion and Implications: Findings underscore the central role of SH in aging, particularly how dynamic changes in social participation, connections, and support relate to cognitive and functional outcomes.

Indexed as

CognitionCohort studyDaily functioningLatent class growth analysisLatent growth curve analysisSocial health

Identifiers

PMID42100167
PMCPMC13147440

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.