ArticleEuropean clinical respiratory journal2026
Cystic fibrosis mental health and wellness questionnaire - factors and properties of a comprehensive CF-specific self-report measure.
Article in European clinical respiratory journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Cystic fibrosis mental health and wellness questionnaire - factors and properties of a comprehensive CF-specific self-report measure.European clinical respiratory journal · 2026Article
- Psychosocial and mental health in cystic fibrosis in the modern era of care: time to evolve.BMJ open respiratory research · 2025Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Existing mental health self-report measures have been criticized for over-simplification, lack of CF-specific focus, susceptibility to measurement reactivity bias, and conflation of symptoms of anxiety and/or depression with CF-related symptoms and/or treatment side effects. The CF Mental Health and Wellness Questionnaire (CFMHWQ) is a 25-item measure assessing CF-specific mental health burden symptoms. Methods: To examine common underlying factors contributing to scores on the CFMHWQ, principal component analysis (PCA) was conducted of all 25 items. We conducted cross-validation of CFMHWQ principal components, examining unadjusted correlations between each principal component, demographic characteristics (age and biological sex), negative affect (mean rank global score combining BDI-II and BAI), psychological flexibility (mean rank global score combining AAQ-II and CFQ), and clinical characteristics. Results: One hundred twenty-three individuals contributed data for the PCA. A 5-factor model provided the most interpretable structure. Factors appeared to correspond to CF role-related concerns, CF symptomatic burden, social impairments due to CF, behavioral compliance, and coping/personality factors. Greater CF role impairments, behavioral adherence, symptom burden, social impairments, and poorer CF coping are all associated with greater negative affect. Similarly, greater levels of psychological flexibility are associated with lower CF role impairments, social impairments, behavioral adherence, and higher CF coping. Older age was associated with better behavioral adherence, but otherwise demographic factors were unrelated to CFMHWQ scores. Conclusions: The CFMHWQ is a promising new self-report measure of CF-specific mental health burden, which associates with negative affect and psychological flexibility. Older age was associated with better behavioral adherence. Finally, more than half reported having undergone a medical procedure they experienced as traumatic, highlighting the importance of measuring the mental health burden of CF. Given the CF-specific nature of items and overfamiliarity with existing measures, we encourage the addition of the CFMHWQ by the CF community.
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Registered trials
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