ReviewFrontiers in physiology2026
Impacts of genetic selection on satellite cell function in poultry.
Review in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Over the past several decades, intensive genetic selection has markedly increased growth rate, breast muscle yield, and production efficiency in commercial broilers. These gains have been accompanied by substantial changes in muscle organization, physiology, metabolism, and cellular regulation. Satellite cells, the resident muscle stem cells, play a key role in posthatch muscle growth by supplying nuclei to adjacent growing myofibers, thereby supporting the muscle hypertrophy process. This review summarizes the role of satellite cells in poultry muscle development and discusses how genetic selection for rapid muscle growth has reshaped satellite cell proliferation, differentiation, molecular profiles, and functional heterogeneity, with important consequences for muscle growth and quality. Moreover, increasing evidence suggests that changes in satellite cell function associated with genetic selection may contribute to the development of breast muscle myopathies, particularly wooden breast in broiler chickens. Moving forward, continued refinement of poultry production systems will benefit from deeper insights into satellite cell biology to support efficient muscle growth while reducing the occurrence of muscle myopathies.
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