Evidence map›Paper›PMID 42099899›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2026

Identification of

Xue Fu, Jiawei Dong, Jian Yang, Xiaotian Zhang, Shangkun Cai, Yiwei Zhang, Shenglong Lv, Meng Zhang

Abstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xue FuDepartment of Emergency, Hebei Medical University Third Hospital, Shijiazhuang, 050051, People's Republic of China.
Jiawei DongDepartment of Thoracic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, 050051, People's Republic of China.
Jian YangDepartment of Thoracic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, 050051, People's Republic of China.
Xiaotian ZhangDepartment of Thoracic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, 050051, People's Republic of China.
Shangkun CaiDepartment of Thoracic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, 050051, People's Republic of China.
Yiwei ZhangDepartment of Thoracic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, 050051, People's Republic of China.
Shenglong LvDepartment of Thoracic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, 050051, People's Republic of China.
Meng ZhangDepartment of Thoracic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, 050051, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The processes of pyroptosis, apoptosis, and necroptosis (PANoptosis) play a crucial role in the development of chronic obstructive pulmonary disease (COPD). Our objective is to explore potential PANoptosis-related genes in COPD. Methods: Human COPD-related transcriptomic datasets (GSE8545, GSE20257, GSE11784 and GSE1650) were retrieved from the Gene Expression Omnibus (GEO). First, based on GSE8545 dataset, candidate genes were identified using differentially expressed gene (DEG) analysis, Weighted Gene Co-expression Network Analysis (WGCNA), Least Absolute Shrinkage and Selection Operator (LASSO) regression, and Support Vector Machine-Recursive Feature Elimination (SVM-RFE). Subsequently, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were conducted for the relevant genes. Results: Three PANoptosis-related hub genes ( Conclusion: We identified

Indexed as

Lipopolysaccharide ReceptorsLungPulmonary Disease, Chronic ObstructiveApoptosisBiomarkersDatabases, GeneticGene Expression ProfilingGene Regulatory NetworksGenetic MarkersHumansPredictive Value of TestsSignal TransductionTranscriptomeBiomarkersCD14 protein, humanGenetic MarkersLipopolysaccharide ReceptorsCD14COPDimmune infiltrationPANoptosistarget drugs

Identifiers

PMID42099899
PMCPMC13144298

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.