Evidence map›Paper›PMID 42099892›Full record

ArticleFrontiers in health services2026

Posttraumatic stress in young children at risk for maltreatment: a causal data science analysis.

Glenn N Saxe, Leah J Morales, Sisi Ma, Mehmet Urgurbil, Constantin Aliferis

Abstract read
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Article in Frontiers in health services, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Glenn N SaxeDepartment of Child and Adolescent Psychiatry, New York University School of Medicine, New York, NY, United States.
Leah J MoralesDepartment of Child and Adolescent Psychiatry, New York University School of Medicine, New York, NY, United States.
Sisi MaInstitute for Health Informatics, University of Minnesota, Minneapolis, MN, United States.
Mehmet UrgurbilInstitute for Health Informatics, University of Minnesota, Minneapolis, MN, United States.
Constantin AliferisInstitute for Health Informatics, University of Minnesota, Minneapolis, MN, United States.

Funding

The Center on Causal Data Science for Child Maltreatment Prevention (the CHAMP Center)P50HD112027 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Mary C Acri · 2023 to 2026
$7.7M
Computational Models for the Prediction and Prevention of Child Traumatic Stress - Resubmission - 1R01MH119114 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SAXE, GLENN N · 2019 to 2022
$2.6M
NICHD NIH HHS P50 HD112027NIMH NIH HHS R01 MH119114
6 · The paper itself

Abstract

Introduction: This article features the application of Causal Data Science (CDS) methods to determine the mechanism for Posttraumatic Stress (PTS) in young, maltreated children, in order to advance knowledge for prevention. Advances in prevention require research that identifies causal factors, but the scientific literature that would inform the identification of causes are almost exclusively based on the application of correlational methods to observational data. Causal inferences from such research will frequently be in error. We conducted the present study to explore the application of CDS methods as an alternative-or a supplement-to experimental methods, which can rarely be applied in human research on causal factors for PTS. Methods: A data processing pipeline that integrates state-of-the-art CDS algorithms was applied to an existing observational, longitudinal data set collected by the Consortium for Longitudinal Studies in Child Abuse and Neglect (LONGSCAN). This data set contains a sample of 1,354 children who were identified in infancy to early childhood as being maltreated or at risk. Results: A causal network model of 251 variables (nodes) and 818 bivariate relations (edges) was discovered, revealing four direct causes (Emotional Maltreatment at age 0-4, Physical Assault at age 8, Feeling of Safety at age 8, and Witnessing Violence at age 8) and two direct effects (Negative Self-Image and Severe Assault from a Non-Caregiver at age 8) of PTS at age 8, within a network containing a broad diversity of causal pathways. Discussion: These results indicate that CDS methods show promise for research on the complex etiology of PTS in young, maltreated children.

Indexed as

causalitychildrendata sciencemaltreatmentpost-traumatic stress

Identifiers

PMID42099892
PMCPMC13143975

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.