Evidence map›Paper›PMID 42099860›Full record

ArticleCurrent research in food science2026

Piperlonguminine inhibits hen egg white lysozyme amyloid fibril formation and mitigates amyloid fibril-induced hepatocellular damage.

Gangqiang Liu, Haotian Yang, Zhuoheng Xie, Zerui Wang, Shilin Sun, Junyao Chu, Qianrui Zhang, Yalin Dong, Guirong Borijihan, Yun Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current research in food science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gangqiang LiuSchool of Pharmacy, Hebei Medical University, Shijiazhuang, 050017, China.
Haotian YangSchool of Pharmacy, Hebei Medical University, Shijiazhuang, 050017, China.
Zhuoheng XieSchool of Pharmacy, Hebei Medical University, Shijiazhuang, 050017, China.
Zerui WangSchool of Pharmacy, Hebei Medical University, Shijiazhuang, 050017, China.
Shilin SunSchool of Pharmacy, Hebei Medical University, Shijiazhuang, 050017, China.
Junyao ChuSchool of Pharmacy, Hebei Medical University, Shijiazhuang, 050017, China.
Qianrui ZhangSchool of Pharmacy, Hebei Medical University, Shijiazhuang, 050017, China.
Yalin DongSchool of Pharmacy, Hebei Medical University, Shijiazhuang, 050017, China.
Guirong BorijihanCollege of Chemistry and Environment, Huhhot Minzu College, Huhhot, 010051, China.
Yun HuangSchool of Pharmacy, Hebei Medical University, Shijiazhuang, 050017, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein misfolding and aggregation into amyloid fibrils (AFs) are critical issues associated with protein stability during food processing and storage, as well as with pathological damage in organisms. Hen egg white lysozyme (HEWL), a widely used protein in egg products, meat processing, and food preservation, serves as a classical model for investigating amyloidogenesis. Piperlonguminine (PPR), a low-toxicity bioactive alkaloid from

Indexed as

Amyloid fibrilsFood protein aggregationHen egg white lysozymeHepatocellular damageMolecular interactionPiperlonguminine

Identifiers

PMID42099860
PMCPMC13147845

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.