ReviewJPRAS open2026
Breast implant explantation and capsulectomy in symptomatic patients. Is there any improvement with the procedure? Systematic review and meta-analysis.
Review in JPRAS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There has been a significant increase in the surgical procedures for breast implant removal and capsulectomies, primarily because of the fear that implants may cause cancer, breast implant-related illness (BII), or systemic symptoms associated with breast implants (SSBI).
methodsWe conducted a systematic review and meta-analysis according to PRISMA criteria. The main objective of the study was to identify the causes of explantation and capsulectomy and whether the procedure improves the alterations attributable to breast implants. We did not include patients diagnosed with BIA-ALCs in this study. We divided the patients into two groups: the first comprised BII/SSBI and ASIA syndrome; the second group comprised granulomas, hypercalcemia, renal damage, and respiratory dysfunction.
resultsAfter explantation and capsulectomy, most patients in the first group did not achieve complete improvement and the degree was moderate, whereas patients in the second group achieved significant improvement. The patients with ASIA achieved partial improvement and required additional treatment. We found significant differences in the symptoms between BII/SSBI and ASIA. The incidence of breast implant-associated comorbidities was not related to the implant length of stay, capsular contracture, or rupture; age < 50 years was a significant factor in the incidence of BII/SSBI.
conclusionThere was considerable heterogeneity in the literature; therefore, the results of this study should be interpreted with caution.
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