Evidence map›Paper›PMID 42099373›Full record

ReviewCureus2026

Chronic Plaque Psoriasis as a Predictor of Spinal Osteoproliferation on Magnetic Resonance Imaging (MRI).

Kristen Tamsil, Madison Gackle, Srujani Das, Raisa Suha, Zarin Kothari, Simran Agarwal, John T Schwartz

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kristen TamsilOsteopathic Medicine, Touro University College of Osteopathic Medicine, Vallejo, USA.
Madison GackleOrthopaedic Surgery, Arizona College of Osteopathic Medicine, Glendale, USA.
Srujani DasOrthopaedic Surgery, William Carey University College of Osteopathic Medicine, Hattiesburg, USA.
Raisa SuhaMedicine, Stony Brook University, Stony Brook, USA.
Zarin KothariOrthopaedic Surgery, Wayne State University School of Medicine, Detroit, USA.
Simran AgarwalOrthopedic Surgery, Ross University School of Medicine, Barbados, USA.
John T SchwartzOrthopedic Surgery, Valley Consortium for Medical Education, Modesto, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic plaque psoriasis is a systemic inflammatory condition that extends beyond the skin and has been linked to musculoskeletal changes, including excessive bone formation along the spine. Emerging evidence indicates that individuals with psoriasis are more likely to demonstrate spinal bony overgrowth than those without the disease. Although biologically plausible mechanisms have been proposed to explain this relationship, there is currently no clear framework for translating the association into clinical decision-making. Existing practice recommendations do not specify which patients might benefit from spinal magnetic resonance imaging (MRI) evaluation, nor do they clarify whether identifying early, asymptomatic changes influences long-term outcomes. The routine use of MRI is further complicated by its expense, variability in imaging techniques, and the need for adequate clinical suspicion before testing. As a result, its role in standard psoriasis management remains ill-defined. Further investigation is needed to establish uniform imaging criteria, identify high-risk patient subgroups, and assess outcomes over time to determine whether earlier identification of spinal involvement can alter disease trajectories. For now, the value of this review lies in drawing attention to the observed relationship between psoriasis and spinal bone formation, while emphasizing the substantial gaps that must be addressed before this knowledge can inform evidence-based screening or management approaches.

Indexed as

axial spondyloarthritisdermatologyenthesophytemagnetic resonance (mr)mriorthopaedicsosteoproliferationpsoriasisrheumatology

Identifiers

PMID42099373
PMCPMC13148456

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.